Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4qfy DCP Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4qfy DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.213
4bzb DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.167
4qfx DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.162
4to4 DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.117
4qg1 DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.062
4qfz TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.050
4to2 DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.021
4to3 DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 1.021
4to0 DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.970
4to1 DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.970
4qg0 DUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.921
4mz7 DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.915
4to5 DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.905
4tny DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.884
4to6 TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.871
4rxp DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.834
4rxs TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.805
4rxr DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.793
4tnz TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.769
4rxq DUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.755
4to0 DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.697
1ols TDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.681
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.680
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.670
3exf TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.667
3exf TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.667
3orl AGSSerine/threonine protein kinase / 0.663
1ky2 GNPGTP-binding protein YPT7 / 0.659
1n2g APCPantothenate synthetase 6.3.2.1 0.657
1n75 ATPGlutamate--tRNA ligase 6.1.1.17 0.653
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.653
4fvq ATPTyrosine-protein kinase JAK2 / 0.653
3myk ANPMyosin-2 heavy chain / 0.651
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.651
4g5q GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.651
1njf ADPDNA polymerase III subunit tau 2.7.7.7 0.650