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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4qa0 SHH Histone deacetylase 8 3.5.1.98

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4qa0 SHHHistone deacetylase 8 3.5.1.98 1.061
5dc5 B3NHistone deacetylase 8 3.5.1.98 0.797
4qa2 SHHHistone deacetylase 8 3.5.1.98 0.772
4qa1 B3NHistone deacetylase 8 3.5.1.98 0.769
2v5x V5XHistone deacetylase 8 3.5.1.98 0.741
2puc GUNHTH-type transcriptional repressor PurR / 0.658