sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 1.322 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.927 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.873 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.872 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.865 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.850 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.840 | |
| 4u7w | NDP | MxaA | / | 0.838 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.837 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.835 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.832 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.829 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.829 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.826 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.824 | |
| 1sny | NAP | LD36273p | / | 0.823 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.822 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.821 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.818 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.813 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.810 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.808 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.805 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.805 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.804 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.799 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.797 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.793 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.792 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.790 | |
| 4kwh | NAP | Reductase homolog | / | 0.790 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.789 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.789 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.787 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.787 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.785 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.785 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.784 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.781 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.780 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.779 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.779 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.778 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.774 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.773 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.771 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.769 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.769 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.768 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.767 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.767 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.767 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.767 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.766 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.766 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.765 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.765 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.765 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.765 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.762 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.762 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.762 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.761 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.761 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.758 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.757 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.757 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.757 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.756 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.756 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.756 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.756 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.755 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.754 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.753 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.753 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.753 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.753 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.752 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.750 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.750 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.749 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.747 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.746 | |
| 2x86 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.746 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.746 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.745 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.745 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.744 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.743 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.743 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.742 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.741 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.741 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.740 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.740 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.740 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.740 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.740 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.739 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.739 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.738 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.738 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.737 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.736 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.736 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.736 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.735 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.735 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.735 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.735 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.734 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.734 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.733 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.733 | |
| 3mje | NDP | AmphB | / | 0.733 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.732 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.730 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.730 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.730 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.729 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.729 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.729 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.728 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.727 | |
| 5d2e | NAP | MlnE | / | 0.727 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.726 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.725 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.725 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.723 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.722 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.720 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.718 | |
| 4hxy | NDP | Plm1 | / | 0.718 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.717 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.717 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.717 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.715 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.715 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.715 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.714 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.711 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.711 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.711 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.711 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.710 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.710 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.709 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.707 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.707 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.707 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.707 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.706 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.706 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.705 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.705 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.704 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.704 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.703 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.703 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.700 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.699 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.697 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.696 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.695 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.695 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.695 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.694 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.694 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.693 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.693 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.692 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.692 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.692 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.691 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.691 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.690 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.690 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.689 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.689 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.685 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.685 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.684 | |
| 3uce | NDP | Dehydrogenase | / | 0.684 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.683 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.682 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.680 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.679 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.678 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.678 | |
| 1rpn | NDP | GDP-mannose 4,6-dehydratase | / | 0.677 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.677 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.676 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.676 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.674 | |
| 1i36 | NAP | Conserved protein | / | 0.674 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.673 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.672 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.672 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.671 | |
| 4xb2 | NDP | 319aa long hypothetical homoserine dehydrogenase | / | 0.669 | |
| 3pef | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.668 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.667 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.667 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.666 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.666 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.666 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.665 | |
| 4qxm | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.665 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.664 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.664 | |
| 5ijz | NAP | NADP-specific glutamate dehydrogenase | 1.4.1.4 | 0.664 | |
| 1j5p | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.663 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.663 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.663 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.663 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.662 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.662 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.662 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.661 | |
| 3pdu | NAP | Glyoxalate/3-oxopropanoate/4-oxobutanoate reductase | / | 0.660 | |
| 3sju | NDP | Keto reductase | / | 0.659 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.659 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.658 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.658 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.657 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.657 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.657 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.657 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.656 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.655 | |
| 3hwr | NDP | 2-dehydropantoate 2-reductase | / | 0.655 | |
| 4y1b | NAP | AntE | / | 0.655 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.654 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.653 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.652 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.652 | |
| 3bmo | NAP | Pteridine reductase | / | 0.651 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.651 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.650 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.650 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.650 |