Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ple CPS Nuclear receptor subfamily 5 group A member 2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ple CPSNuclear receptor subfamily 5 group A member 2 / 1.032
1n35 CH1RNA-directed RNA polymerase lambda-3 2.7.7.48 0.744
1n38 U3HRNA-directed RNA polymerase lambda-3 2.7.7.48 0.744
1nmd ATPMajor actin / 0.744
1wet GUNHTH-type transcriptional repressor PurR / 0.744
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.744
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.744
2jey HLOAcetylcholinesterase 3.1.1.7 0.744
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.744
2zs9 ADPPantothenate kinase 2.7.1.33 0.744
3cwq ADPParA family chromosome partitioning protein / 0.744
3f8p NADNADH oxidase/thioredoxin reductase / 0.744
3f8r NAPNADH oxidase/thioredoxin reductase / 0.744
3fzf ATPHeat shock cognate 71 kDa protein / 0.744
3ypi PGHTriosephosphate isomerase 5.3.1.1 0.744
3zzn ADPL-lactate dehydrogenase / 0.744
4e5l DBHPolymerase acidic protein / 0.744
5bnt NAPAspartate-semialdehyde dehydrogenase 1.2.1.11 0.744
1xu7 CPSCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.739
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.728
3w5r LOAVitamin D3 receptor / 0.721
2b01 TUDPhospholipase A2, major isoenzyme 3.1.1.4 0.705
3w5q 3KLVitamin D3 receptor / 0.700
2qo5 CHDFatty acid-binding protein 10-A, liver basic / 0.698
3cav CI23-oxo-5-beta-steroid 4-dehydrogenase / 0.688
4q0a 4OAVitamin D3 receptor A / 0.687
2mm3 CHOGastrotropin / 0.685
1p8d CO1Oxysterols receptor LXR-beta / 0.677
2azy CHDPhospholipase A2, major isoenzyme 3.1.1.4 0.677
3w1w CHDFerrochelatase, mitochondrial 4.99.1.1 0.676
2ft9 CHDFatty acid-binding protein 2, liver / 0.673
1kdk DHTSex hormone-binding globulin / 0.666
2b00 GCHPhospholipase A2, major isoenzyme 3.1.1.4 0.666
1f5f DHTSex hormone-binding globulin / 0.665
1kdm DHTSex hormone-binding globulin / 0.665
1t5z DHTAndrogen receptor / 0.665
4j6d TESCytochrome P450 monooxygenase / 0.665
2jn3 JN3Fatty acid-binding protein, liver / 0.663
4oed DHTAndrogen receptor / 0.661
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.660
1h48 C5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4.6.1.12 0.660
1yra GDPGPN-loop GTPase PAB0955 / 0.660
2b03 TUDPhospholipase A2, major isoenzyme 3.1.1.4 0.660
2hru ADPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.660
2puf GUNHTH-type transcriptional repressor PurR / 0.660
2xtn GTPGTPase IMAP family member 2 / 0.660
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.660
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.660
4at2 ASDPossible succinate dehydrogenase / 0.660
4cdg ADPBloom syndrome protein 3.6.4.12 0.660
4nxv GDPMitochondrial dynamics protein MID51 / 0.660
4o3m ADPBloom syndrome protein 3.6.4.12 0.660
1d2s DHTSex hormone-binding globulin / 0.656
2k62 ITLFatty acid-binding protein, liver / 0.655
2qpy DHTAndrogen receptor / 0.652
2pit DHTAndrogen receptor / 0.650
3s79 ASDAromatase 1.14.14.14 0.650
4k7a DHTAndrogen receptor / 0.650