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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4o2l GTP GTP-binding protein Rheb

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4o2l GTPGTP-binding protein Rheb / 1.128
3mjh GTPRas-related protein Rab-5A / 1.022
4o25 GTPGTP-binding protein Rheb / 1.017
2ffq GSPRas-related protein Rab-6B / 0.991
3k9l GNPGTPase HRas / 0.984
1vg8 GNPRas-related protein Rab-7a / 0.981
1d5c GDPGTPase (Rab6) / 0.972
2rgc GNPGTPase HRas / 0.968
3kko GNPRas-related protein M-Ras / 0.968
4dlx GNPGTPase HRas / 0.967
1yzq GNPRas-related protein Rab-6A / 0.966
1xtr GNPGTP-binding protein Rheb / 0.965
4dlz GNPGTPase HRas / 0.965
3lbh GNPGTPase HRas / 0.963
2fe4 GDPRas-related protein Rab-6B / 0.962
3rs4 GNPGTPase HRas / 0.962
4kvg GTPRas-related protein Rap-1A / 0.962
4qxa GTPRas-related protein Rab-9A / 0.955
2ce2 GDPGTPase HRas / 0.952
4k81 GTPGTPase HRas / 0.952
2c5l GTPGTPase HRas / 0.947
1z0d GDPRas-related protein Rab-5C / 0.946
1zc3 GNPRas-related protein Ral-A / 0.946
4dlw GNPGTPase HRas / 0.946
1uad GNPRas-related protein Ral-A / 0.941
4lhw GNPRas-related protein Rab-8A / 0.937
4o2r GDPGTP-binding protein Rheb / 0.937
2rge GNPGTPase HRas / 0.936
3kud GDPGTPase HRas / 0.936
3i3s GNPGTPase HRas / 0.933
3k8y GNPGTPase HRas / 0.933
4dlt GNPGTPase HRas / 0.933
3lbi GNPGTPase HRas / 0.932
3rs5 GNPGTPase HRas / 0.932
3rs7 GNPGTPase HRas / 0.932
4dlv GNPGTPase HRas / 0.932
2gil GTPRas-related protein Rab-6A / 0.931
4epx GDPGTPase KRas / 0.929
1zc4 GNPRas-related protein Ral-A / 0.927
3tso GNPRas-related protein Rab-25 / 0.925
4dso GSPGTPase KRas / 0.925
3oes GNPGTPase RhebL1 / 0.924
4l9s GDPGTPase HRas / 0.923
4q02 GDPGTPase KRas / 0.923
2rgb GNPGTPase HRas / 0.920
2rgg GNPGTPase HRas / 0.919
3oiu GNPGTPase HRas / 0.918
3v4f GNPGTPase HRas / 0.917
4dls GNPGTPase HRas / 0.916
4dsn GCPGTPase KRas / 0.916
4xvq GNPGTPase HRas / 0.916
3oiw GNPGTPase HRas / 0.912
3tgp GNPGTPase HRas / 0.911
4lpk GDPGTPase KRas / 0.910
4xsg GSPTransforming protein RhoA / 0.907
1m7b GTPRho-related GTP-binding protein RhoE / 0.906
1tu3 GNPRas-related protein Rab-5A / 0.905
1z0a GDPRas-related protein Rab-2A / 0.904
5b2z GNPGTPase HRas / 0.903
3rab GNPRas-related protein Rab-3A / 0.902
1cxz GSPTransforming protein RhoA / 0.900
4hdo GNPRas-related protein Rap-1b / 0.899
5c46 GSPRas-related protein Rab-11A / 0.898
1t91 GTPRas-related protein Rab-7a / 0.897
3lbn GNPGTPase HRas / 0.897
4hdq GNPRas-related protein Rap-1b / 0.897
4ql3 GDPGTPase KRas / 0.897
4xvr GNPGTPase HRas / 0.896
3bc1 GNPRas-related protein Rab-27A / 0.894
2xtz GSPGuanine nucleotide-binding protein alpha-1 subunit / 0.893
1n6l GTPRas-related protein Rab-5A / 0.892
4xoi GTPTransforming protein RhoA / 0.889
4wa7 GDPGTPase KRas / 0.888
1e96 GTPRas-related C3 botulinum toxin substrate 1 / 0.885
3x1w GDPRas-related protein Rap-1b / 0.883
3cx8 GSPGuanine nucleotide-binding protein subunit alpha-13 / 0.878
3tnf GNPRas-related protein Rab-8A / 0.878
4ldj GDPGTPase KRas / 0.878
2fju GSPRas-related C3 botulinum toxin substrate 1 / 0.877
4nyi GNPGTPase HRas / 0.875
1oix GDPRas-related protein Rab-11A / 0.871
4g0n GNPGTPase HRas / 0.870
2bme GNPRas-related protein Rab-4A / 0.869
3law GNPRas-related protein Rab-7a / 0.869
4dsu GDPGTPase KRas / 0.869
1xts GTPGTP-binding protein Rheb / 0.868
3oiv GNPGTPase HRas / 0.868
4l9w GNPGTPase HRas / 0.868
4lhv GDPRas-related protein Rab-8A / 0.868
4rkf GNPRas-related protein Rab-3 / 0.867
1z2a GDPRas-related protein Rab-23 / 0.866
3l8y GNPGTPase HRas / 0.866
1g17 GNPRas-related protein SEC4 / 0.864
4dvg GSPRho family GTPase / 0.864
2ic5 GDPRas-related C3 botulinum toxin substrate 3 / 0.863
3qbt GNPRas-related protein Rab-8A / 0.862
1mh1 GNPRas-related C3 botulinum toxin substrate 1 / 0.861
1yu9 GNPRas-related protein Rab-4A / 0.861
2w2v GTPRas-related C3 botulinum toxin substrate 2 / 0.861
4pao GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.861
3e5h GNPRas-related protein Rab-28 / 0.859
1a2b GSPTransforming protein RhoA / 0.858
1gia GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.858
1x1r GDPRas-related protein M-Ras / 0.857
4dxa GSPRas-related protein Rap-1b / 0.856
2cl6 CAGGTPase HRas / 0.855
3dt2 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.855
3dt4 GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.855
4q03 GDPGTPase KRas / 0.855
4tq9 GDPGTPase KRas / 0.855
3bbp GTPRas-related protein Rab-6A / 0.854
3kuc GDPRas-related protein Rap-1A / 0.853
1lfd GNPGTPase HRas / 0.852
1yra GDPGPN-loop GTPase PAB0955 / 0.851
4d0l GSPRas-related protein Rab-11A / 0.851
1gil GSPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.850
2gcp GSPRho-related GTP-binding protein RhoC / 0.850
3ddc GNPGTPase HRas / 0.849
3x1z GNPRas-related protein Rap-1b / 0.848
1kmq GNPTransforming protein RhoA / 0.846
2dpx GDPGTP-binding protein RAD / 0.846
1zbd GTPRas-related protein Rab-3A / 0.844
1z0f GDPRas-related protein Rab-14 / 0.843
3vhx GTPADP-ribosylation factor 6 / 0.843
1s1c GNPTransforming protein RhoA / 0.841
2j0v GDPRac-like GTP-binding protein ARAC7 / 0.840
4cym GCPRas-related protein Rab-32 / 0.840
3ref GDPRho family GTPase / 0.839
1g16 GDPRas-related protein SEC4 / 0.838
3th5 GNPRas-related C3 botulinum toxin substrate 1 / 0.835
3rs0 GNPGTPase HRas / 0.834
4nyj GNPGTPase HRas / 0.834
1ow3 GDPTransforming protein RhoA / 0.833
3a58 GNPGTP-binding protein RHO1 / 0.833
3rsl GNPGTPase HRas / 0.832
4l8g GDPGTPase KRas / 0.832
4uj3 GNPRas-related protein Rab-11A / 0.832
3kz1 GSPTransforming protein RhoA / 0.831
4js0 GNPCell division control protein 42 homolog / 0.831
2ov2 GCPRas-related C3 botulinum toxin substrate 3 / 0.829
1ake AP5Adenylate kinase / 0.828
2p2l GDPRas-related C3 botulinum toxin substrate 1 / 0.827
4pan GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.827
1ky2 GNPGTP-binding protein YPT7 / 0.826
2ic5 GNPRas-related C3 botulinum toxin substrate 3 / 0.825
4gzl GNPRas-related C3 botulinum toxin substrate 1 / 0.825
4lv6 GDPGTPase KRas / 0.824
5di3 GNPADP-ribosylation factor-like protein 3 / 0.824
3cph GDPRas-related protein SEC4 / 0.823
2gvd GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.820
1wdt GTPElongation factor G (EF-G-2) / 0.819
3kkq GDPRas-related protein M-Ras / 0.819
3pit GNPRas-related protein M-Ras / 0.819
4ncl GDPEukaryotic translation initiation factor 5B / 0.817
2fah GDPPhosphoenolpyruvate carboxykinase [GTP], mitochondrial 4.1.1.32 0.816
4luc GDPGTPase KRas / 0.816
5d3q GDPDynamin-1 3.6.5.5 0.815
3sbe GNPRas-related C3 botulinum toxin substrate 1 / 0.814
2g0n GDPRas-related C3 botulinum toxin substrate 3 / 0.813
4epw GDPGTPase KRas / 0.812
4mit GTPRho-related protein racC / 0.811
4ylg GDPADP-ribosylation factor 1, putative / 0.811
2qme GCPRas-related C3 botulinum toxin substrate 3 / 0.810
1cs4 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.809
4goj GNPADP-ribosylation factor-like protein 3 / 0.809
2w2x GSPRas-related C3 botulinum toxin substrate 2 / 0.807
3r9x GNPGTPase Era / 0.806
4g01 GDPRas-related protein RABF2b / 0.806
4m0l GDPTranslation initiation factor 2 subunit gamma / 0.805
5dif GNPGTP-binding nuclear protein Ran / 0.804
3cx6 GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.803
3sbd GNPRas-related C3 botulinum toxin substrate 1 / 0.802
4y0v GDPADP-ribosylation factor 1, putative / 0.801
1zd9 GDPADP-ribosylation factor-like protein 8A / 0.797
2fna ADPUncharacterized protein / 0.791
3bb3 GDPTranslocase of chloroplast 33, chloroplastic 3.6.5 0.789
3ums GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.789
1wa5 GTPGTP-binding nuclear protein Ran / 0.785
4itr GDPCell division control protein 42 homolog / 0.785
1cul GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.782
1u0h GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.782
1z2c GNPRho-related GTP-binding protein RhoC / 0.782
2y65 ADPKinesin heavy chain / 0.781
4ymu ATPABC-type polar amino acid transport system, ATPase component / 0.780
1fmw ATPMyosin-2 heavy chain / 0.779
1rrg GDPADP-ribosylation factor 1 / 0.779
2l0x GDPGTP-binding protein Rheb / 0.779
4gzm GSPRas-related C3 botulinum toxin substrate 1 / 0.779
3onw GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.778
1w5s ADPORC1-type DNA replication protein 2 / 0.777
1w5t ANPORC1-type DNA replication protein 2 / 0.777
4uj5 GNPRas-related protein Rab-11A / 0.777
2qen ADPWalker-Type ATPase / 0.776
2bku GTPGTP-binding nuclear protein Ran / 0.775
2j5x GSPADP-ribosylation factor 6 / 0.775
2olr ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.774
3b1x GNPFerrous iron transport protein B / 0.774
3tqc ADPPantothenate kinase / 0.774
5dha GNPGTP-binding nuclear protein Ran / 0.774
3a6p GTPGTP-binding nuclear protein Ran / 0.772
2c96 ATPPsp operon transcriptional activator / 0.771
1h65 GDPTranslocase of chloroplast 34 3.6.5 0.770
4jsy GTPMetallophosphoesterase / 0.770
4yqf GDPSeptin-9 / 0.770
4a1z ADPKinesin-like protein KIF11 / 0.769
1a4r GNHCell division control protein 42 homolog / 0.768
2rgx AP5Adenylate kinase / 0.767
1gp2 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.765
4lrw GDPGTPase KRas / 0.765
1zcb GDPGuanine nucleotide-binding protein subunit alpha-13 / 0.764
2x7e ADPKinesin-like protein KIF11 / 0.764
3w3z GTPGTP-binding nuclear protein Ran / 0.764
1bof GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.763
2uyi ADPKinesin-like protein KIF11 / 0.762
1ank ANPAdenylate kinase / 0.761
4asu ADPATP synthase subunit alpha, mitochondrial / 0.761
2pg2 ADPKinesin-like protein KIF11 / 0.759
2x2r ADPKinesin-like protein KIF11 / 0.759
4r43 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.758
1ibr GNPGTP-binding nuclear protein Ran / 0.756
2eck ADPAdenylate kinase / 0.756
3l9h ADPKinesin-like protein KIF11 / 0.756
2zet GTPRas-related protein Rab-27B / 0.755
1jx2 ADPMyosin-2 heavy chain / 0.754
1yrs ADPKinesin-like protein KIF11 / 0.754
2bbw GP5Adenylate kinase 4, mitochondrial / 0.754
3fmo ADPATP-dependent RNA helicase DDX19B 3.6.4.13 0.754
3ftq GNPSeptin-2 / 0.753
3pcr GTPADP-ribosylation factor 6 / 0.752
4pfp ADPUnconventional myosin-VI / 0.752
2fg5 GNPRas-related protein Rab-31 / 0.751
3ea5 GDPGTP-binding nuclear protein Ran / 0.751
3t1t GDPProbable gliding protein mglA / 0.751
4hi0 GDPUrease accessory protein UreG / 0.751
4ihq ADPConserved Archaeal protein / 0.751
4pjj ADPUnconventional myosin-VI / 0.751
1w0k ADPATP synthase subunit alpha, mitochondrial / 0.750
1w0k ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.750
3tkl GTPRas-related protein Rab-1A / 0.750
3zia ATPATP synthase subunit alpha, mitochondrial / 0.750
5jlj GNPGTP-binding nuclear protein Ran / 0.750
3eg5 GNPCell division control protein 42 homolog / 0.749
4cf7 ADPAdenylate kinase / 0.749
1got GDPGuanine nucleotide-binding protein G(t) subunit alpha-1 / 0.748
2gks ADPProbable bifunctional SAT/APS kinase 2.7.1.25 0.748
4z54 GDPNeuronal-specific septin-3 / 0.748
1sdm ADPKinesin heavy chain-like protein / 0.747
1ytm ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.747
2ql6 ADPNicotinamide riboside kinase 1 / 0.747
1e79 ATPATP synthase subunit alpha, mitochondrial / 0.743
1e79 ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.743
1xmv ADPProtein RecA / 0.743
3cob ADPKinesin heavy chain-like protein / 0.743
4g5q GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.743
4yer ADPAntibiotic ABC transporter, ATP-binding protein, putative / 0.743
2gm1 ADPKinesin-like protein KIF11 / 0.741
3wyg GTPGTP-binding nuclear protein GSP1/CNR1 / 0.741
5l3r GCPCell division protein FtsY homolog, chloroplastic / 0.741
1azt GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.740
1mma ADPMyosin-2 heavy chain / 0.738
2v7q ATPATP synthase subunit alpha, mitochondrial / 0.738
2v7q ATPATP synthase subunit beta, mitochondrial 3.6.3.14 0.738
1e79 ADPATP synthase subunit alpha, mitochondrial / 0.737
1e79 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.737
1p9w ANPType II secretion system protein E / 0.737
2g1q ADPKinesin-like protein KIF11 / 0.737
2zr9 DTPProtein RecA / 0.737
4qos ADPPsp operon transcriptional activator / 0.737
2qtv GNPSmall COPII coat GTPase SAR1 3.6.5 0.736
4x8l AP5Adenylate kinase / 0.736
4pk4 ADPUnconventional myosin-VI / 0.735
5bn3 ADPV-type ATP synthase alpha chain / 0.735
5bn3 ADPNEQ263 / 0.735
1p3d ANPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.734
1wbb ADPDNA mismatch repair protein MutS / 0.734
1svw GTPProbable GTP-binding protein EngB / 0.733
1am4 GNPCell division control protein 42 homolog / 0.732
5i67 GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.732
3c15 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.731
4jl6 ADPAdenylate kinase / 0.731
4obe GDPGTPase KRas / 0.731
5ftc ADPTPR domain protein / 0.731
2c9o ADPRuvB-like 1 3.6.4.12 0.730
3tlx ADPAdenylate kinase 2 / 0.730
1k6m AGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 2.7.1.105 0.729
3k3b ADPKinesin-like protein KIF11 / 0.729
4a51 ADPKinesin-like protein KIF11 / 0.729
1bif AGS6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.7.1.105 0.727
1gqy ACPUDP-N-acetylmuramate--L-alanine ligase 6.3.2.8 0.727
4zca ADPKinesin-like protein KIF11 / 0.727
5k5z ANPUncharacterized protein / 0.727
1okk GCPSignal recognition particle protein / 0.726
1okk GCPSignal recognition particle receptor FtsY / 0.726
4oi4 ATPmRNA cleavage and polyadenylation factor CLP1 / 0.726
1g6o ADPCag alpha / 0.725
3k1j ADPATP-dependent protease Lon / 0.725
4hse ADPChaperone protein ClpB / 0.725
4jky ADPAdenylate kinase / 0.725
5aun ADPIron-sulfur cluster carrier protein / 0.724
2q3f GNPRas-related GTP-binding protein D / 0.723
3kji ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.723
4a28 ADPKinesin-like protein KIF11 / 0.723
1w5t ADPORC1-type DNA replication protein 2 / 0.722
2jiz ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.722
2q2z ADPKinesin-like protein KIF11 / 0.722
4cvm ANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.722
4qbh AP5Adenylate kinase / 0.722
2bif ANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 2.7.1.105 0.721
4pjk ADPMyosin-2 heavy chain / 0.721
1in5 ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.720
1svl ADPLarge T antigen 3.6.4 0.720
2fl2 ADPKinesin-like protein KIF11 / 0.720
1mmg AGSMyosin-2 heavy chain / 0.719
3q5d GDPAtlastin-1 3.6.5 0.719
1i4l GDPRas-related C3 botulinum toxin substrate 1 / 0.718
1sq5 ADPPantothenate kinase 2.7.1.33 0.718
3thy ADPDNA mismatch repair protein Msh2 / 0.718
4tl9 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.718
5hpy GDPTransforming protein RhoA / 0.718
1ny5 ADPTranscriptional regulator (NtrC family) / 0.717
1rj9 GCPSignal recognition particle receptor FtsY / 0.717
3r9i ADPSeptum site-determining protein MinD / 0.717
4b7b ADPKinesin-like protein KIF11 / 0.717
1bmf ADPATP synthase subunit alpha, mitochondrial / 0.715
1bmf ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.715
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.714
2py7 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.714
2zfi ADPKinesin-like protein KIF1A / 0.714
2zts ADPUncharacterized protein / 0.714
4jl5 ADPAdenylate kinase / 0.714
5irn ADPNucleotide binding oligomerization domain containing 2 / 0.714
3zvm ADPBifunctional polynucleotide phosphatase/kinase 2.7.1.78 0.713
5cyo GDPSeptin-9 / 0.713
1fnn ADPORC1-type DNA replication protein / 0.712
1xnj ADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 2.7.1.25 0.712
1y3a GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.712
3myk ANPMyosin-2 heavy chain / 0.712
2xae ADPKinesin-like protein KIF11 / 0.711
3ea0 ATPATPase, ParA family / 0.710
3ieu GDPGTPase Era / 0.710
3moh GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.710
4bzq ADPBifunctional enzyme CysN/CysC 2.7.1.25 0.710
4iok ADPFormate--tetrahydrofolate ligase / 0.710
5fl3 ADPPili retraction protein PilT / 0.710
4c0b ATPmRNA cleavage and polyadenylation factor CLP1 / 0.709
4idn GNPAtlastin-1 3.6.5 0.709
4v02 ATPSite-determining protein / 0.708
2pc9 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.706
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.706
2db3 ANPATP-dependent RNA helicase vasa, isoform A 3.6.4.13 0.705
3qe0 GDPGuanine nucleotide-binding protein G(i) subunit alpha-1 / 0.705
2zpa ADPtRNA(Met) cytidine acetyltransferase TmcA / 0.704
4jjz ADPFormate--tetrahydrofolate ligase / 0.704
1w1w AGSStructural maintenance of chromosomes protein 1 / 0.703
4oi2 ADPProtein clpf-1 / 0.703
2v1x ADPATP-dependent DNA helicase Q1 3.6.4.12 0.702
4ma4 ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.702
4wpu GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.702
1bmf ANPATP synthase subunit alpha, mitochondrial / 0.700
1bmf ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.700
1k5d GNPGTP-binding nuclear protein Ran / 0.700
2dr3 ADPUPF0273 protein PH0284 / 0.700
4ys0 ADPProtein translocase subunit SecA / 0.700
4cei ANPATP-dependent helicase/deoxyribonuclease subunit B 3.1 0.699
5ftf ADPTPR domain protein / 0.699
3adc ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.698
2jlr ANPGenome polyprotein 3.4.21.91 0.697
1ofh ADPATP-dependent protease ATPase subunit HslU / 0.696
1yhn GTPRas-related protein Rab-7a / 0.696
2axn ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 / 0.696
2dwp ACP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.696
2msc GDPMHC class I alpha chain / 0.696
2xau ADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP43 3.6.4.13 0.696
4ww0 ADPATP-dependent zinc metalloprotease FtsH / 0.696
2jj2 ADPATP synthase subunit alpha, mitochondrial / 0.695
2jj2 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.695
2zrj AGSProtein RecA / 0.695
4iei ADPGene 2 protein / 0.695
1os1 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.694
1xms ANPProtein RecA / 0.694
2hf8 GSPProbable hydrogenase nickel incorporation protein HypB / 0.694
4cvl ACPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase / 0.694
1e1q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.693
3qbv GDPCell division control protein 42 homolog / 0.693
4nh0 ATPESX secretion system protein EccC / 0.693
1q3h ANPCystic fibrosis transmembrane conductance regulator / 0.692
2qf2 GDPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.692
3oeh ANPATP synthase subunit alpha, mitochondrial / 0.692
3pfi ADPHolliday junction ATP-dependent DNA helicase RuvB / 0.692
3tjz GNPADP-ribosylation factor 1 / 0.692
2jj2 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.691
4d81 ADPAAA ATPase, central domain protein / 0.691
4db1 ANPMyosin-7 / 0.691
4ko8 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.691
3c41 ANPAmino acid ABC transporter / 0.690
3hu3 AGSTransitional endoplasmic reticulum ATPase 3.6.4.6 0.690
4tlc AGSCircadian clock protein kinase KaiC 2.7.11.1 0.690
1svm ATPLarge T antigen 3.6.4 0.689
4ohx ADPProtein clpf-1 / 0.689
4tle AGSCircadian clock protein kinase KaiC 2.7.11.1 0.689
2o8b ADPDNA mismatch repair protein Msh2 / 0.688
4ike ADPAdenylate kinase / 0.686
4qnr ATPPsp operon transcriptional activator / 0.686
2ck3 ANPATP synthase subunit alpha, mitochondrial / 0.685
2ck3 ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.685
3dm5 GDPSignal recognition particle 54 kDa protein / 0.685
1z6t ADPApoptotic protease-activating factor 1 / 0.683
2ad5 ADPCTP synthase / 0.682
2v7q ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.682
3bos CDPRegulatory inactivation of DnaA Hda protein / 0.682
3d8b ADPFidgetin-like protein 1 3.6.4 0.682
2iut AGSDNA translocase FtsK / 0.681
2olq ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.681
3l1c ADPProtein claret segregational / 0.681
4jld ADPAdenylate kinase / 0.681
4tl7 ATPCircadian clock protein kinase KaiC 2.7.11.1 0.681
3c14 GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short / 0.680
3pyz ANPDihydrofolate synthase/folylpolyglutamate synthase / 0.680
4tl8 AGSCircadian clock protein kinase KaiC 2.7.11.1 0.680
1mez GDPAdenylosuccinate synthetase isozyme 1 / 0.679
2xsz ATPRuvB-like 2 3.6.4.12 0.679
4tld AGSCircadian clock protein kinase KaiC 2.7.11.1 0.678
4ap0 ADPKinesin-like protein KIF11 / 0.676
1aq2 ATPPhosphoenolpyruvate carboxykinase (ATP) / 0.675
1h8h ADPATP synthase subunit alpha, mitochondrial / 0.675
1h8h ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.675
4gp6 ADPMetallophosphoesterase / 0.675
4i1v ADPDephospho-CoA kinase / 0.674
3qpv ADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 2.7.1.105 0.673
3sop GDPNeuronal-specific septin-3 / 0.673
4bec ATPType I restriction enzyme EcoR124II R protein 3.1.21.3 0.672
3a4l ANPL-seryl-tRNA(Sec) kinase 2.7.1.164 0.671
2hld ANPATP synthase subunit alpha, mitochondrial / 0.670
2hld ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.670
2iuu ADPDNA translocase FtsK / 0.670
4c2u ANPDNA helicase / 0.670
4cdg ADPBloom syndrome protein 3.6.4.12 0.670
2q2y ADPKinesin-like protein KIF11 / 0.669
4ag5 ADPType IV secretory pathway VirB4 components-like protein / 0.669
4xvu ATPATPase GET3 / 0.669
2dft ADPShikimate kinase 2.7.1.71 0.668
1gwn GTPRho-related GTP-binding protein RhoE / 0.667
3kb1 ADPIron-sulfur cluster carrier protein / 0.666
4dzz ADPPlasmid partitioning protein ParF / 0.666
4idp GNPAtlastin-1 3.6.5 0.666
4tl6 ANPCircadian clock protein kinase KaiC 2.7.11.1 0.666
3nbz GTPGTP-binding nuclear protein Ran / 0.665
3wyf GTPGTP-binding nuclear protein / 0.664
3oee ANPATP synthase subunit alpha, mitochondrial / 0.663
3oee ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.663
4o3m ADPBloom syndrome protein 3.6.4.12 0.663
3aez GDPPantothenate kinase 2.7.1.33 0.662
4h1v GNPDynamin-1-like protein 3.6.5.5 0.661
4l16 ADPFidgetin-like protein 1 3.6.4 0.661
2j0s ANPEukaryotic initiation factor 4A-III 3.6.4.13 0.660
2xto GDPGTPase IMAP family member 2 / 0.660
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.660
2zro ADPProtein RecA / 0.659
4tlb AGSCircadian clock protein kinase KaiC 2.7.11.1 0.659
4wou GDPPhosphoenolpyruvate carboxykinase [GTP] / 0.658
1sxj AGSReplication factor C subunit 1 / 0.657
2cls GTPRho-related GTP-binding protein Rho6 / 0.657
2jj1 ANPATP synthase subunit alpha, mitochondrial / 0.657
2jj1 ADPATP synthase subunit alpha, mitochondrial / 0.657
2jj1 ADPATP synthase subunit beta, mitochondrial 3.6.3.14 0.657
1sxj ADPReplication factor C subunit 5 / 0.656
2osb AP5Adenylate kinase / 0.656
4ww4 ADPRuvB-like helicase / 0.656
1e1q ANPATP synthase subunit alpha, mitochondrial / 0.654
1e1q ANPATP synthase subunit beta, mitochondrial 3.6.3.14 0.654
1xef ATPAlpha-hemolysin translocation ATP-binding protein HlyB / 0.654
3jvv ACPTwitching mobility protein / 0.653
3q9l ATPSeptum site-determining protein MinD / 0.652
1esn ANPPantothenate kinase 2.7.1.33 0.651
1nly AGSCag alpha / 0.651
1w7k ADPDihydrofolate synthase/folylpolyglutamate synthase 6.3.2.12 0.651
4eht ADP2-hydroxyisocaproyl-CoA dehydratase activator / 0.651
5cyp GSPSeptin-9 / 0.650