Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4o1m NAD Enoyl-acyl carrier reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4o1m NADEnoyl-acyl carrier reductase / 1.091
1vrw NAIEnoyl-ACP reductase / 0.857
3uic NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.834
5koi NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.821
2wyv NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.809
2nq8 ZIDEnoyl-ACP reductase / 0.806
3r3s NADPutative oxidoreductase / 0.784
1xg5 NAPDehydrogenase/reductase SDR family member 11 / 0.762
5jyd NADShort chain dehydrogenase / 0.759
2dkn NAI3-alpha-hydroxysteroid dehydrogenase / 0.747
1cyd NDPCarbonyl reductase [NADPH] 2 1.1.1.184 0.745
4m87 NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.744
2gdz NAD15-hydroxyprostaglandin dehydrogenase [NAD(+)] 1.1.1.141 0.740
3w8f NAD3-hydroxybutyrate dehydrogenase / 0.739
4oxy NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.739
2aqi NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.737
2ekp NAD2-deoxy-D-gluconate 3-dehydrogenase / 0.732
4clo NAPPteridine reductase / 0.732
4dti NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.729
3rj9 NADAlcohol dehydrogenase 1.1.1.1 0.728
3w8d NAD3-hydroxybutyrate dehydrogenase / 0.728
2aqh NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.726
2d1y NADOxidoreductase, short-chain dehydrogenase/reductase family / 0.726
2ztm NADD(-)-3-hydroxybutyrate dehydrogenase / 0.725
4bmv NAPShort-chain dehydrogenase / 0.725
3d3w NAPL-xylulose reductase 1.1.1.10 0.723
4yai NAIC alpha-dehydrogenase / 0.723
4yag NAIC alpha-dehydrogenase / 0.722
2nv6 ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.721
3bmo NAPPteridine reductase / 0.718
1g0n NDPTetrahydroxynaphthalene reductase 1.1.1.252 0.716
3aw9 NADNAD-dependent epimerase/dehydratase / 0.716
2ztl NADD(-)-3-hydroxybutyrate dehydrogenase / 0.715
3ijr NADOxidoreductase, short chain dehydrogenase/reductase family / 0.715
1eny NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.714
1v35 NAIEnoyl-ACP reductase / 0.714
3zu2 NAIEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.713
3sxp NADADP-L-glycero-D-mannoheptose-6-epimerase / 0.711
3vdq NAD3-hydroxybutyrate dehydrogenase / 0.711
1geg NADDiacetyl reductase [(S)-acetoin forming] 1.1.1.304 0.710
2idz ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.710
3w8e NAD3-hydroxybutyrate dehydrogenase / 0.710
2ag5 NAD3-hydroxybutyrate dehydrogenase type 2 / 0.708
2q2v NADBeta-D-hydroxybutyrate dehydrogenase / 0.708
4zju NADEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.708
3oey NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.707
2bfo NDPPteridine reductase 1 1.5.1.33 0.706
3h4v NAPPteridine reductase 1 1.5.1.33 0.706
3of2 NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.706
3tn7 NJPShort-chain alcohol dehydrogenase / 0.706
4z3d NDPCarbonyl reductase [NADPH] 1 1.1.1.184 0.706
2o23 NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.705
3rj5 NADAlcohol dehydrogenase 1.1.1.1 0.702
2aq8 NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.701
3oew NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.701
2aqk NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.700
3p19 NDPPutative blue fluorescent protein / 0.699
2ntj P1HEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.695
4trn NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.695
3ak4 NADNADH-dependent quinuclidinone reductase / 0.694
1e6w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.693
1rwb NADGlucose 1-dehydrogenase 1.1.1.47 0.693
2c29 NAPDihydroflavonol 4-reductase / 0.693
3l77 NJPShort-chain alcohol dehydrogenase / 0.692
3bhi NAPCarbonyl reductase [NADPH] 1 1.1.1.184 0.690
1n5d NDPCarbonyl reductase [NADPH] 1 / 0.689
1bdb NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase / 0.688
2c59 NADGDP-mannose 3,5-epimerase 5.1.3.18 0.688
2h9i EADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.688
2yw9 NAPEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.688
3rue NADUDP-N-acetylglucosamine 4-epimerase / 0.686
4hp8 NAP2-deoxy-D-gluconate 3-dehydrogenase / 0.685
2ieb ZIDEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.683
2p5y NADUDP-glucose 4-epimerase / 0.682
4b79 NADProbable short-chain dehydrogenase / 0.681
1x7h NDPPutative ketoacyl reductase 1.3.1 0.680
3gy0 NAPNAD(P)-dependent oxidoreductase / 0.680
3ruc NADUDP-N-acetylglucosamine 4-epimerase / 0.680
4dqu NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.680
1e3w NAD3-hydroxyacyl-CoA dehydrogenase type-2 1.1.1.35 0.679
4iqg NAPShort-chain dehydrogenase/reductase SDR / 0.679
2nnl NAPDihydroflavonol 4-reductase 1.1.1.219 0.678
3nug NADPyridoxal 4-dehydrogenase 1.1.1.107 0.678
4bgi NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.678
2q1w NADPutative nucleotide sugar epimerase/ dehydratase / 0.677
1pr9 NAPL-xylulose reductase 1.1.1.10 0.676
4bkq NAIEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.676
4fc7 NAPPeroxisomal 2,4-dienoyl-CoA reductase 1.3.1.34 0.676
4o0l NDPNADPH-dependent 3-quinuclidinone reductase / 0.676
5jla NADPutative short-chain dehydrogenase/reductase / 0.676
3ruf NADUDP-N-acetylglucosamine 4-epimerase / 0.675
4dre NAIEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.675
1gco NADGlucose 1-dehydrogenase 1.1.1.47 0.674
1h5q NAPNADP-dependent mannitol dehydrogenase 1.1.1.138 0.674
2zat NAPDehydrogenase/reductase SDR family member 4 1.1.1.184 0.674
3rud NADUDP-N-acetylglucosamine 4-epimerase / 0.674
2bd0 NAPSepiapterin reductase / 0.670
2dte NAIGlucose 1-dehydrogenase related protein / 0.670
4k6f NAPPutative Acetoacetyl-CoA reductase / 0.670
3rua NADUDP-N-acetylglucosamine 4-epimerase / 0.669
4u7w NDPMxaA / 0.669
4bii NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.668
1oaa NAPSepiapterin reductase 1.1.1.153 0.667
3ko8 NADNAD-dependent epimerase/dehydratase / 0.667
3rku NAPNADP-dependent 3-hydroxy acid dehydrogenase / 0.667
3wds NADNADH-dependent quinuclidinone reductase / 0.667
3o26 NDPSalutaridine reductase / 0.666
1enz NADEnoyl-[acyl-carrier-protein] reductase [NADH] 1.3.1.9 0.665
3sju NDPKeto reductase / 0.665
5bt9 NAP3-oxoacyl-(Acyl-carrier-protein) reductase / 0.665
1eno NADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic 1.3.1.9 0.664
1x7g NAPPutative ketoacyl reductase 1.3.1 0.663
5js6 NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.663
1bws NDPGDP-L-fucose synthase / 0.662
1xse NDPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.662
4eue NAITrans-2-enoyl-CoA reductase [NADH] / 0.662
5jsf NAD17-beta-hydroxysteroid dehydrogenase 14 1.1.1 0.662
2ntv P1HEnoyl-[acyl-carrier-protein] reductase [NADH] / 0.660
1ae1 NAPTropinone reductase 1 / 0.659
2bgm NAJSecoisolariciresinol dehydrogenase 1.1.1.331 0.659
2c54 NADGDP-mannose 3,5-epimerase 5.1.3.18 0.659
2yut NAPPutative short-chain oxidoreductase / 0.659
1b16 NAQAlcohol dehydrogenase 1.1.1.1 0.657
4hwk NAPSepiapterin reductase 1.1.1.153 0.657
2ztu NADD(-)-3-hydroxybutyrate dehydrogenase / 0.655
4j7x NAPSepiapterin reductase 1.1.1.153 0.655
4qec NAPElxO / 0.655
4c7k NAPCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.653
3ndr NADPyridoxal 4-dehydrogenase 1.1.1.107 0.652
3o03 NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) / 0.652
2ydx NAPMethionine adenosyltransferase 2 subunit beta / 0.651
1e7q NAPGDP-L-fucose synthase / 0.650
3qrw NDPPutative ketoacyl reductase 1.3.1 0.650