sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ntd | FAD | Thioredoxin reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4ntd | FAD | Thioredoxin reductase | / | 1.340 | |
| 4jn9 | FAD | DepH | / | 1.037 | |
| 3fbs | FAD | Oxidoreductase | / | 1.025 | |
| 4nte | FAD | DepH | / | 0.993 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.891 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.855 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.846 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.827 | |
| 1zmd | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.826 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.826 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.822 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.818 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.817 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.811 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.805 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.804 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.803 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.799 | |
| 2qa1 | FAD | PgaE | / | 0.799 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.798 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.796 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.795 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.793 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.791 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 0.791 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.790 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 0.788 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.787 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.787 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.786 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.785 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.781 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.780 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.779 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.778 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.777 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.777 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.773 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.768 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.767 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.767 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.767 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.766 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.765 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.764 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.763 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.762 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.762 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.761 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.760 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.759 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.758 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.756 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.756 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.756 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.755 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.754 | |
| 4ccr | FAD | Thioredoxin reductase | / | 0.754 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.753 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.752 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.752 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.752 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.752 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.752 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.751 | |
| 3cge | FAD | Coenzyme A disulfide reductase | / | 0.751 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.749 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.749 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.749 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.747 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.747 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.745 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.745 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.744 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.744 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.744 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.743 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.743 | |
| 4tm3 | FAD | KtzI | / | 0.743 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.742 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.742 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.742 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.741 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.741 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.741 | |
| 4icy | FAD | PgaE | / | 0.741 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.740 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.740 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.739 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.739 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.738 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.737 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.737 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.736 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.736 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.735 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.735 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.735 | |
| 2bab | FAD | Putative aminooxidase | / | 0.734 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.734 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.733 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.733 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.732 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.732 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.731 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.731 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.730 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.730 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.730 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.730 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.730 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.729 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.729 | |
| 2wba | FAD | Trypanothione reductase | 1.8.1.12 | 0.728 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.726 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.726 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.725 | |
| 2vq7 | FAD | Putative flavin-containing monooxygenase | / | 0.724 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.724 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.723 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.723 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.722 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.722 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.722 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.721 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.721 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.720 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.720 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.719 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.719 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.719 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.719 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.719 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.719 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.719 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.719 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.719 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.718 | |
| 2wow | FAD | Trypanothione reductase | / | 0.718 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.717 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.716 | |
| 4tm4 | FDA | KtzI | / | 0.715 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.714 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.714 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.714 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.714 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.713 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.713 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.712 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.712 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.711 | |
| 3itj | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.711 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.710 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.710 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.710 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.709 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.709 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.709 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.709 | |
| 3c4a | FAD | Protodeoxyviolaceinate monooxygenase | 1 | 0.708 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.708 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.707 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.707 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.707 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.707 | |
| 4jy2 | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.707 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.706 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.706 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.706 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.706 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.706 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.705 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.705 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.704 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.703 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.703 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.702 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.702 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.702 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.702 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.702 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.701 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.701 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.701 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.700 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.700 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.700 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.699 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.699 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.699 | |
| 1n4u | FAE | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.698 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.698 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 4xwr | FAD | Cholesterol oxidase | 1.1.3.6 | 0.698 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.697 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.697 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.697 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.697 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.697 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.697 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.697 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.696 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.696 | |
| 3gmb | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.696 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.696 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.695 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.695 | |
| 4b64 | FAD | L-ornithine N(5)-monooxygenase | / | 0.695 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.694 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.694 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.693 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.693 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.693 | |
| 1zmc | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.693 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.693 | |
| 4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.693 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.693 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.692 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.692 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.692 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.691 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.691 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.691 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.690 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.690 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.690 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.690 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.689 | |
| 1h6v | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.688 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.688 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.688 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.688 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.688 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.688 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.687 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.687 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.687 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.687 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.687 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.687 | |
| 4jnq | FDA | Thioredoxin reductase | / | 0.687 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.687 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.686 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.686 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.686 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.686 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.686 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.685 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.685 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.685 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.685 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.685 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.685 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.685 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.685 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.685 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.684 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.684 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.684 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.684 | |
| 2iw5 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.683 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.683 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.683 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.683 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.683 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.682 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.682 | |
| 1mxt | FAE | Cholesterol oxidase | 1.1.3.6 | 0.682 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.682 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.682 | |
| 5dju | FMN | NPH1-2 | / | 0.682 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.681 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.681 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.681 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.681 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.680 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.680 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.680 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.680 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.679 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.679 | |
| 2bac | FAD | Putative aminooxidase | / | 0.678 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.678 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.677 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.677 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.677 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.677 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.677 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.676 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.676 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.676 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.675 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.675 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.675 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.674 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.674 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.673 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.673 | |
| 4tm0 | FAD | KtzI | / | 0.673 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.673 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.672 | |
| 2gj3 | FAD | Nitrogen fixation regulatory protein | 2.7.13.3 | 0.671 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.671 | |
| 3gsi | FAD | Dimethylglycine oxidase | 1.5.3.10 | 0.671 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.671 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.671 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.671 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.670 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.670 | |
| 4tlx | FDA | KtzI | / | 0.670 | |
| 2cul | FAD | GidA-related protein | / | 0.669 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.669 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.669 | |
| 2iid | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.668 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.668 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.667 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.667 | |
| 4b66 | FAD | L-ornithine N(5)-monooxygenase | / | 0.667 | |
| 4k5r | FAD | Oxygenase | / | 0.667 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.666 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.666 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.666 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.666 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.666 | |
| 4nev | FAD | Trypanothione reductase | / | 0.666 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.666 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.665 | |
| 3kkj | FAD | Renalase | / | 0.665 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.665 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.665 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.664 | |
| 3fmw | FAD | Oxygenase | / | 0.664 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.664 | |
| 5efw | FMN | NPH1-1 | / | 0.664 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.663 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.663 | |
| 3b6d | FAE | Cholesterol oxidase | 1.1.3.6 | 0.663 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.663 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.663 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.663 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.662 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.662 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.662 | |
| 3rha | FDA | Putrescine oxidase | / | 0.662 | |
| 4cnj | FAD | L-amino acid oxidase | / | 0.662 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.662 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.662 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.660 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.660 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.660 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.660 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.660 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.660 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.660 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.659 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.659 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.659 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.659 | |
| 3sm8 | FNK | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.659 | |
| 4ylf | FAD | Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit homolog | / | 0.659 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.658 | |
| 1t6y | FMN | Riboflavin biosynthesis protein | / | 0.658 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.658 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.658 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.658 | |
| 5djt | FMN | NPH1-2 | / | 0.658 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.657 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.656 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.655 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.655 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.655 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.655 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.655 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.655 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.654 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.654 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.654 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.654 | |
| 2gv8 | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.654 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.654 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.654 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.653 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.653 | |
| 3hjk | FAD | Vivid PAS protein VVD | / | 0.653 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.653 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.652 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.652 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.652 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.651 | |
| 3d72 | FAD | Vivid PAS protein VVD | / | 0.651 | |
| 2jib | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.650 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.650 | |
| 3ue6 | FMN | Aureochrome1 | / | 0.650 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.650 |