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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4nk9 2K5 Fibroblast growth factor receptor 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
4nk9 2K5Fibroblast growth factor receptor 1 / 1.157
4f65 0S9Fibroblast growth factor receptor 1 / 0.768
2fgi PD1Fibroblast growth factor receptor 1 / 0.722
3w16 P9JAurora kinase A 2.7.11.1 0.684
4c61 LMMTyrosine-protein kinase JAK2 / 0.677
4f63 0S7Fibroblast growth factor receptor 1 / 0.673
3lfa 1N1Mitogen-activated protein kinase 14 / 0.672
4nks 2M2Fibroblast growth factor receptor 1 / 0.665
4bdh WVISerine/threonine-protein kinase Chk2 2.7.11.1 0.656
3oct 1N1Tyrosine-protein kinase BTK 2.7.10.2 0.654