sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 1.129 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 1.055 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 1.001 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.986 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.962 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.961 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.943 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.941 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.933 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.930 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.929 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.926 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.920 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.917 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.900 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.897 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.895 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.894 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.894 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.894 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.893 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.892 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.890 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.879 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.876 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.873 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.867 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.865 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.862 | |
| 3sju | NDP | Keto reductase | / | 0.862 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.861 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.861 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.861 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.855 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.854 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.853 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.852 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.850 | |
| 4qec | NAP | ElxO | / | 0.850 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.848 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.848 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.847 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.843 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.841 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.841 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.841 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.838 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.837 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.836 | |
| 1sny | NAP | LD36273p | / | 0.834 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.832 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.832 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.832 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.830 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.830 | |
| 1iy8 | NAD | Levodione reductase | / | 0.829 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.829 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.828 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.828 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.828 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.826 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.825 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.825 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.824 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.824 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.824 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.822 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.819 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.817 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.816 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.815 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.815 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.815 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.814 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.813 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.812 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.811 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.811 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.810 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.810 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.809 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.809 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.808 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.808 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.807 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.806 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.806 | |
| 4qed | NAP | ElxO | / | 0.806 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.805 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.804 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.802 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.800 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.799 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.798 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.797 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.797 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.796 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.796 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.795 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.794 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.794 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.792 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.791 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.790 | |
| 4kwh | NAP | Reductase homolog | / | 0.790 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.789 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.786 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.786 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.786 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.785 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.784 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.784 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.784 | |
| 3wmx | NAD | NAD dependent epimerase/dehydratase | / | 0.783 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.782 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.782 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.781 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.781 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.781 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.779 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.778 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.778 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.778 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.778 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.774 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.773 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.771 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.771 | |
| 4o0l | NDP | NADPH-dependent 3-quinuclidinone reductase | / | 0.771 | |
| 5d2e | NAP | MlnE | / | 0.770 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.762 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.762 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.762 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.762 | |
| 3uce | NDP | Dehydrogenase | / | 0.761 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.760 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.759 | |
| 4hxy | NDP | Plm1 | / | 0.759 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.758 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.757 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.756 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.756 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.755 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.753 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.751 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.750 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.750 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.749 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.749 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.747 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.747 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.743 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.743 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.742 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.742 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.741 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.740 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.739 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.739 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.738 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.738 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.737 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.736 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.735 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.733 | |
| 4bms | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.733 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.733 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.731 | |
| 4u7w | NDP | MxaA | / | 0.731 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.730 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.730 | |
| 4clo | NAP | Pteridine reductase | / | 0.728 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.728 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.727 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.726 | |
| 3a9w | NAD | NDP-sugar epimerase | / | 0.725 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.724 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.723 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.723 | |
| 3bmo | NAP | Pteridine reductase | / | 0.722 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.722 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.720 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.717 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.716 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.716 | |
| 1eq2 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.715 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.715 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.715 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.714 | |
| 3ajr | NAD | NDP-sugar epimerase | / | 0.713 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.713 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.707 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.707 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.707 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.707 | |
| 3mje | NDP | AmphB | / | 0.707 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.707 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.707 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.706 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.705 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.705 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.704 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.704 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.703 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 2x6t | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.702 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.702 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.702 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.702 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.702 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.701 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.701 | |
| 1n7g | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.698 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.696 | |
| 3u4c | NDP | NADPH-dependent reductase BacG | / | 0.693 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.693 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.690 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.688 | |
| 2z1m | NDP | GDP-mannose 4,6-dehydratase | / | 0.688 | |
| 4imp | NDP | Polyketide synthase extender modules 3-4 | / | 0.688 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.687 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.685 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.682 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.682 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.681 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.680 | |
| 3abi | NAD | Uncharacterized protein | / | 0.680 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.679 | |
| 2dt5 | NAD | Redox-sensing transcriptional repressor Rex | / | 0.678 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.678 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.676 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.676 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.675 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.675 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.675 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.674 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.674 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.673 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.672 | |
| 2g76 | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.672 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.672 | |
| 1jki | NAI | Inositol-3-phosphate synthase | 5.5.1.4 | 0.667 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.667 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.667 | |
| 3ec7 | NAD | Inositol 2-dehydrogenase | / | 0.665 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.665 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.662 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.661 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.660 | |
| 4n5n | NAP | Acetoacetyl-CoA reductase | 1.1.1.36 | 0.660 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.659 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.659 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.659 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.658 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.658 | |
| 4id9 | NAD | Putative UDP-glucose 4-epimerase | / | 0.657 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.656 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.655 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.655 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.654 | |
| 1uay | ADN | Oxidoreductase | / | 0.651 | |
| 1psd | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.650 |