Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4mam A12 N5-carboxyaminoimidazole ribonucleotide synthase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4mam A12N5-carboxyaminoimidazole ribonucleotide synthase / 1.101
3eth ATPN5-carboxyaminoimidazole ribonucleotide synthase / 0.797
4c5b ADPD-alanine--D-alanine ligase B 6.3.2.4 0.756
3i12 ADPD-alanine--D-alanine ligase A 6.3.2.4 0.753
3t9e ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.752
2io8 ADPBifunctional glutathionylspermidine synthetase/amidase / 0.747
1z2n ADPInositol-tetrakisphosphate 1-kinase 2.7.1.134 0.729
3k5h ATPPhosphoribosyl-aminoimidazole carboxylase / 0.720
4ffl ADPUncharacterized protein / 0.720
3q1k ADPD-alanine--D-alanine ligase A 6.3.2.4 0.718
3r5f ATPD-alanine--D-alanine ligase / 0.715
1pk8 ATPSynapsin-1 / 0.714
2vqd AP2Biotin carboxylase 6.3.4.14 0.711
5c1p ADPD-alanine--D-alanine ligase / 0.704
2zdg ADPD-alanine--D-alanine ligase / 0.702
1z2p ACPInositol-tetrakisphosphate 1-kinase 2.7.1.134 0.701
4jlb ADPAdenylate kinase / 0.698
4f99 ADPCell division cycle 7-related protein kinase 2.7.11.1 0.696
3g8d ADPBiotin carboxylase 6.3.4.14 0.694
1iah ADPTransient receptor potential cation channel subfamily M member 7 2.7.11.1 0.692
5e9e ANPMyosin heavy chain kinase A 2.7.11.7 0.692
2b9f ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.689
2ioa ADPBifunctional glutathionylspermidine synthetase/amidase / 0.688
2p0a ANPSynapsin-3 / 0.688
4hpt ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.688
4nzo ANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.686
2b9j ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.684
4q4c ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.684
3lmi ATPMyosin heavy chain kinase A 2.7.11.7 0.683
2yw2 ATPPhosphoribosylamine--glycine ligase / 0.680
4uak ADPSerine/threonine-protein kinase MRCK beta 2.7.11.1 0.680
4iak ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.678
4jl8 ADPAdenylate kinase / 0.678
2io7 ANPBifunctional glutathionylspermidine synthetase/amidase / 0.675
3qc9 ADPRhodopsin kinase / 0.672
1px2 ATPSynapsin-1 / 0.671
2d1s SLULuciferin 4-monooxygenase 1.13.12.7 0.671
4dh5 ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.671
3t9f ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.669
1v3s ATPSignaling protein / 0.668
4rx6 ATPNitrogen regulatory PII-like protein / 0.668
3tw6 ADPPyruvate carboxylase / 0.667
4ffm ADPUncharacterized protein / 0.667
3eps ATPIsocitrate dehydrogenase kinase/phosphatase / 0.666
3t99 ADPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.665
4jlp ADPAdenylate kinase / 0.664
4iai ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.663
4zme ADNMyosin heavy chain kinase A 2.7.11.7 0.663
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.662
4h3q ANPMitogen-activated protein kinase 1 2.7.11.24 0.662
2y9q ANPMitogen-activated protein kinase 1 2.7.11.24 0.661
4zgn ATPCell division cycle protein 123 / 0.661
1ig1 ANPDeath-associated protein kinase 1 2.7.11.1 0.660
3vpb ADPGlutamate--LysW ligase ArgX 6.3.2 0.660
3wo0 ADPAlanine--anticapsin ligase / 0.660
4cng SAHSpoU rRNA methylase / 0.660
5c1o ANPD-alanine--D-alanine ligase / 0.660
2hgs ADPGlutathione synthetase 6.3.2.3 0.659
2xul ATPNitrogen regulatory protein P-II / 0.659
4iaf ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.659
1jkl ANPDeath-associated protein kinase 1 2.7.11.1 0.658
1mru AGSSerine/threonine-protein kinase PknB 2.7.11.1 0.658
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.658
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.657
3c4z ADPRhodopsin kinase / 0.656
3ies M24Luciferin 4-monooxygenase 1.13.12.7 0.656
4cnf MTASpoU rRNA methylase / 0.656
4fu0 ADPD-alanine--D-alanine ligase / 0.656
3mey ATPAmino acid--[acyl-carrier-protein] ligase 1 6.2.1.n2 0.655
3t9d ANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 / 0.654
3w8q AGSDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.654
4s26 SAHPhosphomethylpyrimidine synthase, chloroplastic 4.1.99.17 0.654
1m0w ANPGlutathione synthetase 6.3.2.3 0.653
3vqx BLKPyrrolysine--tRNA ligase / 0.653
4s33 ANPMitogen-activated protein kinase 1 2.7.11.24 0.652
4oa9 ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.651
4oxi GAPEnterobactin synthetase component F-related protein / 0.651
2wtk ANPSTE20-related kinase adapter protein alpha / 0.650
4eom ATPCyclin-dependent kinase 2 2.7.11.22 0.650
4ii5 ADPCyclin-dependent kinase 2 2.7.11.22 0.650
4uxx ACPDiacylglycerol kinase 2.7.1.107 0.650