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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4lc7 1WP Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4lc7 1WPBeta-secretase 1 3.4.23.46 0.808
4l7g 1W0Beta-secretase 1 3.4.23.46 0.781
4j1c 1HOBeta-secretase 1 3.4.23.46 0.705
3zki WZVBeta-secretase 2 3.4.23.45 0.689
4j0z 1H5Beta-secretase 1 3.4.23.46 0.678
3zmg 6Z0Beta-secretase 1 3.4.23.46 0.673
4djx 0KQBeta-secretase 1 3.4.23.46 0.670
4l7h 1W1Beta-secretase 1 3.4.23.46 0.669
4h3g 10QBeta-secretase 1 3.4.23.46 0.664
4ha5 13WBeta-secretase 1 3.4.23.46 0.659
3wb4 0B3Beta-secretase 1 3.4.23.46 0.652