Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l65 C2F 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2.1.1.14

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4l65 C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2.1.1.14 1.111
4l64 C2F5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2.1.1.14 0.810
1u22 THG5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 2.1.1.14 0.692
2fmn 4HF5,10-methylenetetrahydrofolate reductase 1.5.1.20 0.657
1dtn APGMandelate racemase / 0.656
2rd5 NLGAcetylglutamate kinase, chloroplastic 2.7.2.8 0.655