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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4l2x YL2 Farnesyl pyrophosphate synthase 2.5.1.10

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4l2x YL2Farnesyl pyrophosphate synthase 2.5.1.10 1.186
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.041
4h5c YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.975
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.958
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.938
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.921
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.869
3icz PB6Farnesyl pyrophosphate synthase / 0.866
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.841
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.834
4dwb 0M7Farnesyl pyrophosphate synthase / 0.812
4dxj 0M9Farnesyl pyrophosphate synthase / 0.809
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.802
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.794
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.778
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.754
2o1o RISPutative farnesyl pyrophosphate synthase / 0.744
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.741
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.733
2z52 H23Geranylgeranyl pyrophosphate synthase / 0.719
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.703
1yq7 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.694
3dyh 721Farnesyl pyrophosphate synthase / 0.694
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.682
4jvj 1MVFarnesyl pyrophosphate synthase 2.5.1.10 0.679
3egt 722Farnesyl pyrophosphate synthase / 0.674
3oab DSTGeranyl diphosphate synthase large subunit / 0.669
4tl6 ANPCircadian clock protein kinase KaiC 2.7.11.1 0.669
2e91 ZOLGeranylgeranyl pyrophosphate synthase / 0.661
1khe GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.659
1mez GDPAdenylosuccinate synthetase isozyme 1 / 0.653
3w2w ATPCRISPR system Cmr subunit Cmr2 / 0.652
4ig8 DTP2'-5'-oligoadenylate synthase 1 / 0.652