Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4k6m SAH Genome polyprotein

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4k6m SAHGenome polyprotein / 0.883
2px2 SAHGenome polyprotein 2.7.7.48 0.846
3emd SFGMethyltransferase / 0.845
3p8z SAHGenome polyprotein 2.1.1.56 0.793
2p3q SAHGenome polyprotein / 0.791
4ctk SAMGenome polyprotein / 0.790
3p97 SAMGenome polyprotein 2.1.1.56 0.789
4ctj SAMGenome polyprotein / 0.789
3eva SAHGenome polyprotein 2.1.1.56 0.781
2nyu SAMrRNA methyltransferase 2, mitochondrial / 0.776
2pxa SAHGenome polyprotein 2.7.7.48 0.776
3evc SAHGenome polyprotein 2.1.1.56 0.774
3evb SAHGenome polyprotein 2.1.1.56 0.770
3eld SFGMethyltransferase / 0.764
3ely SAHMethyltransferase / 0.764
3p8z 36AGenome polyprotein 2.1.1.56 0.759
3elu SAMMethyltransferase / 0.757
5il2 SAHN6-adenosine-methyltransferase 70 kDa subunit / 0.753
3lkz SFGGenome polyprotein / 0.751
2px5 SAHGenome polyprotein 2.7.7.48 0.747
1wg8 SAMRibosomal RNA small subunit methyltransferase H / 0.746
5jjr SAHGenome polyprotein / 0.746
1i9g SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.736
5dto SAHGenome polyprotein / 0.736
1r6a SAHGenome polyprotein 2.7.7.48 0.732
5k7w SAHN6-adenosine-methyltransferase 70 kDa subunit / 0.732
2g1p SAHDNA adenine methylase 2.1.1.72 0.729
5ccx SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.724
2p41 SAHGenome polyprotein / 0.723
2yvl SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.723
2plw SAMRibosomal RNA methyltransferase, putative / 0.717
4uck SAMLarge structural protein / 0.714
1l9k SAHGenome polyprotein 2.7.7.48 0.713
5ccb SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.707
2oy0 SAHGenome polyprotein / 0.705
5il1 SAMN6-adenosine-methyltransferase 70 kDa subunit / 0.704
4n48 SAMCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 2.1.1.57 0.702
2p1d SAHGenome polyprotein 2.7.7.48 0.698
4x7y SAHMycinamicin III 3''-O-methyltransferase 2.1.1.237 0.698
4xvy SAHMycinamicin III 3''-O-methyltransferase 2.1.1.237 0.696
2pwy SAHtRNA (adenine(58)-N(1))-methyltransferase TrmI 2.1.1.220 0.695
2wa2 SAMGenome polyprotein / 0.689
3pt9 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.684
5k7u SAMN6-adenosine-methyltransferase 70 kDa subunit / 0.681
9mht SAHModification methylase HhaI 2.1.1.37 0.681
3tos SAHCalS11 / 0.677
2xbm SAHGenome polyprotein / 0.676
2dpm SAMModification methylase DpnIIA 2.1.1.72 0.674
10mh SAHModification methylase HhaI 2.1.1.37 0.671
2xyr SFGReplicase polyprotein 1ab 2.1.1 0.671
3cbg SAHO-methyltransferase / 0.666
2uyh SAHModification methylase HhaI 2.1.1.37 0.664
4gf5 SAHCalS11 / 0.664
3evg SAHGenome polyprotein 2.1.1.56 0.659
3ldg SAHUncharacterized protein / 0.658