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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jvj 1MV Farnesyl pyrophosphate synthase 2.5.1.10

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jvj 1MVFarnesyl pyrophosphate synthase 2.5.1.10 1.096
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.776
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.770
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.763
3icz PB6Farnesyl pyrophosphate synthase / 0.757
3dyh 721Farnesyl pyrophosphate synthase / 0.745
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.730
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.728
3egt 722Farnesyl pyrophosphate synthase / 0.721
4l2x YL2Farnesyl pyrophosphate synthase 2.5.1.10 0.679
2z4w 749Geranylgeranyl pyrophosphate synthase / 0.674
2pzp ACPFibroblast growth factor receptor 2 / 0.670
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.667
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.660
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.660
4h5c YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.657
3rbm B73Farnesyl pyrophosphate synthase, putative / 0.656
1khe GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.655
4c30 ANPDNA helicase / 0.652
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 0.651