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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jq7 KJQ Epidermal growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jq7 KJQEpidermal growth factor receptor 2.7.10.1 1.074
4jq8 KJ8Epidermal growth factor receptor 2.7.10.1 0.972
4jr3 KJREpidermal growth factor receptor 2.7.10.1 0.954
4jrv KJVEpidermal growth factor receptor 2.7.10.1 0.946
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4wkq IREEpidermal growth factor receptor 2.7.10.1 0.723
3erk SB4Mitogen-activated protein kinase 1 2.7.11.24 0.688
4i23 1C9Epidermal growth factor receptor 2.7.10.1 0.677
2bro DF2Serine/threonine-protein kinase Chk1 2.7.11.1 0.676
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4i22 IREEpidermal growth factor receptor 2.7.10.1 0.660
2itp AEEEpidermal growth factor receptor 2.7.10.1 0.659
2ghl LIBMitogen-activated protein kinase 14 / 0.652