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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jia 1K3 Tyrosine-protein kinase JAK2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jia 1K3Tyrosine-protein kinase JAK2 / 0.798
4aqc 88ATyrosine-protein kinase JAK2 / 0.756
4e5i 0N9Polymerase acidic protein / 0.744
4ji9 1M3Tyrosine-protein kinase JAK2 / 0.694
4d4s BI9Focal adhesion kinase 1 2.7.10.2 0.689
4bbe 3O4Tyrosine-protein kinase JAK2 / 0.663
5dr6 SKEAurora kinase A 2.7.11.1 0.661
4e5f 0N7Polymerase acidic protein / 0.660
4bbf O19Tyrosine-protein kinase JAK2 / 0.659
1vhz APRADP compounds hydrolase NudE 3.6.1 0.651
4qmu SKESerine/threonine-protein kinase 24 2.7.11.1 0.650