Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4jd5 TZD Benzoylformate decarboxylase 4.1.1.7

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4jd5 TZDBenzoylformate decarboxylase 4.1.1.7 1.132
2fwn TDPBenzoylformate decarboxylase 4.1.1.7 1.082
1po7 TZDBenzoylformate decarboxylase 4.1.1.7 1.065
4jub TPPBenzoylformate decarboxylase 4.1.1.7 1.058
4gg1 TZDBenzoylformate decarboxylase 4.1.1.7 1.053
5dgt TZDBenzoylformate decarboxylase 4.1.1.7 1.053
4mq5 TPPBenzoylformate decarboxylase 4.1.1.7 1.051
4qel TZDBenzoylformate decarboxylase 4.1.1.7 1.050
4juf TPPBenzoylformate decarboxylase 4.1.1.7 1.042
4ju9 TZDBenzoylformate decarboxylase 4.1.1.7 1.034
4ju8 TZDBenzoylformate decarboxylase 4.1.1.7 1.033
1bfd TPPBenzoylformate decarboxylase 4.1.1.7 1.025
4mpr TPPBenzoylformate decarboxylase 4.1.1.7 1.025
4gm4 TZDBenzoylformate decarboxylase 4.1.1.7 1.013
4gm1 TZDBenzoylformate decarboxylase 4.1.1.7 1.010
3fzn D7KBenzoylformate decarboxylase 4.1.1.7 1.007
4mzx TZDBenzoylformate decarboxylase 4.1.1.7 1.005
3fsj D7KBenzoylformate decarboxylase 4.1.1.7 0.998
4mpp TZDBenzoylformate decarboxylase 4.1.1.7 0.998
4gm0 TZDBenzoylformate decarboxylase 4.1.1.7 0.995
4k9n TZDBenzoylformate decarboxylase 4.1.1.7 0.968
2v3w TPPBenzoylformate decarboxylase 4.1.1.7 0.939
4k9p TPPBenzoylformate decarboxylase 4.1.1.7 0.936
4juc TPPBenzoylformate decarboxylase 4.1.1.7 0.922
4k9o TPPBenzoylformate decarboxylase 4.1.1.7 0.906
1mcz TDPBenzoylformate decarboxylase 4.1.1.7 0.889
2w93 TPPPyruvate decarboxylase isozyme 1 / 0.826
1y9d TPPPyruvate oxidase 1.2.3.3 0.820
2vk8 TPPPyruvate decarboxylase isozyme 1 / 0.817
4cok TPPPyruvate decarboxylase / 0.814
3hwx TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.797
2q5q TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.796
3oe1 TDLPyruvate decarboxylase 4.1.1.1 0.787
1pow TPPPyruvate oxidase 1.2.3.3 0.784
3lq2 TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.782
2c3p 1TPPyruvate synthase / 0.781
2ihu TP9N(2)-(2-carboxyethyl)arginine synthase / 0.777
2ji6 TPWOxalyl-CoA decarboxylase 4.1.1.8 0.770
2c31 TZDOxalyl-CoA decarboxylase 4.1.1.8 0.767
1pox TPPPyruvate oxidase 1.2.3.3 0.764
2vk4 TPPPyruvate decarboxylase 4.1.1.1 0.763
2ezt TDMPyruvate oxidase 1.2.3.3 0.762
1ols TDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.761
3iae D7KBenzaldehyde lyase / 0.761
5ej9 TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.761
2qta TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.759
2pan TDPGlyoxylate carboligase 4.1.1.47 0.758
5eja TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.757
1rp7 TZDPyruvate dehydrogenase E1 component 1.2.4.1 0.755
1ni4 TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial 1.2.4.1 0.752
1ni4 TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial 1.2.4.1 0.752
2q5o TPWIndole-3-pyruvate decarboxylase 4.1.1.74 0.750
3lq4 TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.750
5c4i TPPOxalate oxidoreductase subunit alpha / 0.746
5c4i TPPOxalate oxidoreductase subunit beta / 0.746
1pvd TPPPyruvate decarboxylase isozyme 1 / 0.745
1pyd TDPPyruvate decarboxylase isozyme 1 / 0.745
2ez9 TDKPyruvate oxidase 1.2.3.3 0.741
2j9f THV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.735
2j9f THV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial 1.2.4.4 0.735
5eso TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.732
5esd TDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.729
2ji7 OXTOxalyl-CoA decarboxylase 4.1.1.8 0.726
4zp1 TPPPyruvate decarboxylase 4.1.1.1 0.724
1jsc TPPAcetolactate synthase catalytic subunit, mitochondrial 2.2.1.6 0.723
2g25 TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.722
5ej7 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.722
1umc TDP2-oxoisovalerate dehydrogenase subunit alpha 1.2.4.4 0.720
1umc TDP2-oxoisovalerate dehydrogenase subunit beta 1.2.4.4 0.720
2g28 TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.717
5ej6 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.716
2ag0 TPPBenzaldehyde lyase / 0.711
2jib TPPOxalyl-CoA decarboxylase 4.1.1.8 0.711
5ej4 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.709
2uz1 TPPBenzaldehyde lyase / 0.708
2o1s TDP1-deoxy-D-xylulose-5-phosphate synthase 2.2.1.7 0.704
1ozh HE3Acetolactate synthase, catabolic 2.2.1.6 0.703
2jlc TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.702
2x7j TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.700
3d7k D7KBenzaldehyde lyase / 0.696
1v11 TDP2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial 1.2.4.4 0.694
3eya TDPPyruvate dehydrogenase [ubiquinone] 1.2.5.1 0.694
5exd TPPOxalate oxidoreductase subunit alpha / 0.692
5exd TPPOxalate oxidoreductase subunit beta / 0.692
2jla TPP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.691
5ej8 TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase / 0.691
2c3y HTLPyruvate synthase / 0.689
2qtc TDKPyruvate dehydrogenase E1 component 1.2.4.1 0.689
2iea TDPPyruvate dehydrogenase E1 component 1.2.4.1 0.677
1ay0 TPPTransketolase 1 2.2.1.1 0.676
3ahj TPPProbable phosphoketolase / 0.674
2c42 TPPPyruvate synthase / 0.670
2ag1 TPPBenzaldehyde lyase / 0.669
2r8o T5XTransketolase 1 / 0.667
1gpu THDTransketolase 1 2.2.1.1 0.666
2pda TPPPyruvate synthase / 0.666
3m6l TPPTransketolase / 0.662
3duf R1TPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.661
3duf R1TPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.661
3iaf TPPBenzaldehyde lyase / 0.660
2iht TPPN(2)-(2-carboxyethyl)arginine synthase / 0.658
3m34 TPPTransketolase / 0.658
5ahk TPPAcetolactate synthase II, large subunit / 0.658
1upa TPPN(2)-(2-carboxyethyl)arginine synthase / 0.657
1upb TPPN(2)-(2-carboxyethyl)arginine synthase / 0.657
1w88 TDPPyruvate dehydrogenase E1 component subunit alpha 1.2.4.1 0.655
1w88 TDPPyruvate dehydrogenase E1 component subunit beta 1.2.4.1 0.655
3zhr TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.654
3rim TPPTransketolase 2.2.1.1 0.653
3zhq TPPMultifunctional 2-oxoglutarate metabolism enzyme 1.2.4.2 0.653
3tgp GNPGTPase HRas / 0.652
1tkb N1TTransketolase 1 2.2.1.1 0.650