Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4j17 1HQ Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4j17 1HQBeta-secretase 1 3.4.23.46 0.980
4j1e 1HMBeta-secretase 1 3.4.23.46 0.919
4j1c 1HOBeta-secretase 1 3.4.23.46 0.876
4j0z 1H5Beta-secretase 1 3.4.23.46 0.867
4j0v 1H7Beta-secretase 1 3.4.23.46 0.853
4j1h 1HJBeta-secretase 1 3.4.23.46 0.838
4bfd 8T3Beta-secretase 1 3.4.23.46 0.829
3zmg 6Z0Beta-secretase 1 3.4.23.46 0.822
4j1k 1HGBeta-secretase 1 3.4.23.46 0.817
4j0p 1H8Beta-secretase 1 3.4.23.46 0.802
4j1i 1HHBeta-secretase 1 3.4.23.46 0.793
4j0y 1H6Beta-secretase 1 3.4.23.46 0.784
3zov WZVBeta-secretase 1 3.4.23.46 0.780
4j1f 1HLBeta-secretase 1 3.4.23.46 0.778
3zki WZVBeta-secretase 2 3.4.23.45 0.762
4j0t 6T9Beta-secretase 1 3.4.23.46 0.749
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
3zks WZVBeta-secretase 2 3.4.23.45 0.728
4l7g 1W0Beta-secretase 1 3.4.23.46 0.684
3wb4 0B3Beta-secretase 1 3.4.23.46 0.670
3zlq 6T9Beta-secretase 2 3.4.23.45 0.659
4frs 0V6Beta-secretase 1 3.4.23.46 0.658
4ha5 13WBeta-secretase 1 3.4.23.46 0.655