sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 1.258 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.948 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.936 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.933 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.920 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.918 | |
| 3pgx | NAD | Uncharacterized NAD-dependent oxidoreductase MAP_4146 | / | 0.905 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.900 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.900 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.898 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.892 | |
| 3tsc | NAD | Uncharacterized protein | / | 0.888 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.888 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.886 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.882 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.882 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.878 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.878 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.875 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.873 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.868 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.864 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.863 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.862 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.860 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.859 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.859 | |
| 1geg | NAD | Diacetyl reductase [(S)-acetoin forming] | 1.1.1.304 | 0.857 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.855 | |
| 3ak4 | NAD | NADH-dependent quinuclidinone reductase | / | 0.854 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.852 | |
| 4kwh | NAP | Reductase homolog | / | 0.850 | |
| 3sju | NDP | Keto reductase | / | 0.849 | |
| 1u7t | TDT | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.844 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.842 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.841 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.841 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.839 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.838 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.836 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.835 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.835 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.834 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.832 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.832 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.828 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.826 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.825 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.824 | |
| 3tn7 | NJP | Short-chain alcohol dehydrogenase | / | 0.824 | |
| 5ig2 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.822 | |
| 2ekp | NAD | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.818 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.814 | |
| 1oaa | NAP | Sepiapterin reductase | 1.1.1.153 | 0.812 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.812 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.811 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.810 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.809 | |
| 1nfr | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.808 | |
| 3geg | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.805 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.805 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.804 | |
| 3ru7 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.804 | |
| 1nff | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.803 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.803 | |
| 3rku | NAP | NADP-dependent 3-hydroxy acid dehydrogenase | / | 0.801 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.799 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.798 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.797 | |
| 4fn4 | NAD | Short chain dehydrogenase | / | 0.796 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.795 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.794 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.794 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.792 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.792 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.791 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.791 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.790 | |
| 4pvd | NDP | NADPH-dependent methylglyoxal reductase GRE2 | / | 0.790 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.789 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.788 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.788 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.787 | |
| 1sny | NAP | LD36273p | / | 0.782 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.782 | |
| 2p5y | NAD | UDP-glucose 4-epimerase | / | 0.782 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.782 | |
| 4dc1 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.782 | |
| 2wsb | NAD | Galactitol dehydrogenase | / | 0.781 | |
| 3rj9 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.781 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.780 | |
| 2ztu | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.780 | |
| 3rj5 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.780 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.777 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.777 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.777 | |
| 1w4z | NAP | Putative ketoacyl reductase | 1.3.1 | 0.774 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.772 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.770 | |
| 4rf2 | NAP | NADPH dependent R-specific alcohol dehydrogenase | / | 0.768 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.767 | |
| 5jyd | NAD | Short chain dehydrogenase | / | 0.766 | |
| 2bd0 | NAP | Sepiapterin reductase | / | 0.765 | |
| 4qed | NAP | ElxO | / | 0.764 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.762 | |
| 3uce | NDP | Dehydrogenase | / | 0.762 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.758 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.758 | |
| 3lu1 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.757 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.757 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.756 | |
| 1xkq | NDP | Uncharacterized protein | / | 0.756 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.756 | |
| 3oew | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.756 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.755 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.754 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.754 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.753 | |
| 4lis | NAD | UDP-glucose 4-epimerase (Eurofung) | / | 0.752 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.751 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.751 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.750 | |
| 4qec | NAP | ElxO | / | 0.750 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.749 | |
| 2dkn | NAI | 3-alpha-hydroxysteroid dehydrogenase | / | 0.748 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.746 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.744 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.743 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.740 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.740 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.739 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.739 | |
| 2b35 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.739 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.739 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.739 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.737 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.737 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.736 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.736 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.735 | |
| 2gdz | NAD | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | 1.1.1.141 | 0.735 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.734 | |
| 1zem | NAD | Xylitol dehydrogenase | / | 0.733 | |
| 3rua | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.733 | |
| 4clo | NAP | Pteridine reductase | / | 0.731 | |
| 1kvr | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.730 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.730 | |
| 4i5e | NAP | Alclohol dehydrogenase/short-chain dehydrogenase | / | 0.730 | |
| 1b16 | NAQ | Alcohol dehydrogenase | 1.1.1.1 | 0.729 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.728 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.727 | |
| 3l77 | NJP | Short-chain alcohol dehydrogenase | / | 0.726 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.726 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.726 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.725 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 2ntj | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.724 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.723 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.721 | |
| 3sxp | NAD | ADP-L-glycero-D-mannoheptose-6-epimerase | / | 0.720 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.720 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.719 | |
| 4ej0 | NAP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.719 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.718 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.718 | |
| 4idg | NAD | Putative UDP-glucose 4-epimerase | / | 0.717 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.716 | |
| 2c54 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.716 | |
| 2ntv | P1H | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.716 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.714 | |
| 2nv6 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.712 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.709 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.708 | |
| 4bii | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.707 | |
| 1w8d | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.706 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.706 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.706 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.703 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.702 | |
| 1iy8 | NAD | Levodione reductase | / | 0.702 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.702 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.702 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.701 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.700 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.700 | |
| 3o4r | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.699 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.699 | |
| 5d2e | NAP | MlnE | / | 0.699 | |
| 1b14 | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.697 | |
| 1nah | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.697 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.696 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.695 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.694 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.692 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.691 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.690 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.690 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.688 | |
| 3bmo | NAP | Pteridine reductase | / | 0.688 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.686 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.686 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.685 | |
| 2bgm | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.684 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.684 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.684 | |
| 2i9p | NAD | 3-hydroxyisobutyrate dehydrogenase, mitochondrial | 1.1.1.31 | 0.683 | |
| 3rue | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.683 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.682 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.681 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.680 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.679 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.678 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.676 | |
| 2bfo | NDP | Pteridine reductase 1 | 1.5.1.33 | 0.675 | |
| 4nbu | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.675 | |
| 3pvz | NAD | UDP-N-acetylglucosamine 4,6-dehydratase | / | 0.673 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.671 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.669 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.668 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.667 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.667 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.667 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.666 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.663 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.663 | |
| 1ahh | NAD | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.662 | |
| 1fk8 | NAD | 3-alpha-hydroxysteroid dehydrogenase/carbonyl reductase | 1.1.1.50 | 0.660 | |
| 1w73 | NAP | 2,4-dienoyl-CoA reductase, mitochondrial | 1.3.1.34 | 0.660 | |
| 2b69 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.660 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.660 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.658 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.657 | |
| 1i3l | NAD | UDP-glucose 4-epimerase | / | 0.657 | |
| 1n7h | GDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.657 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.657 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.656 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.656 | |
| 2ydx | NAP | Methionine adenosyltransferase 2 subunit beta | / | 0.655 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.654 | |
| 2yw9 | NAP | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.654 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.653 | |
| 3qvs | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.653 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.653 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.652 | |
| 1j5p | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.652 | |
| 1o9j | NAD | Aldehyde dehydrogenase, cytosolic 1 | 1.2.1.3 | 0.652 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.651 | |
| 3qvx | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.650 |