Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hys 1BJ Mitogen-activated protein kinase 8 2.7.11.24

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4hys 1BJMitogen-activated protein kinase 8 2.7.11.24 0.906
4izy 1J2Mitogen-activated protein kinase 8 2.7.11.24 0.839
4hyu 1BKMitogen-activated protein kinase 8 2.7.11.24 0.835
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
2z7l S91Mitogen-activated protein kinase 1 2.7.11.24 0.716
3cjf SAVVascular endothelial growth factor receptor 2 2.7.10.1 0.680
4d4s BI9Focal adhesion kinase 1 2.7.10.2 0.663