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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4hx5 19V Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4hx5 19VCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 1.472
2ilt NN1Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.714
3ch6 311Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.655
4hfr 14MCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.652