Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ha5 13W Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ha5 13WBeta-secretase 1 3.4.23.46 0.778
4l7g 1W0Beta-secretase 1 3.4.23.46 0.671
3zmg 6Z0Beta-secretase 1 3.4.23.46 0.667
4o3m ADPBloom syndrome protein 3.6.4.12 0.662
3wb4 0B3Beta-secretase 1 3.4.23.46 0.661
1n35 CH1RNA-directed RNA polymerase lambda-3 2.7.7.48 0.660
1n38 U3HRNA-directed RNA polymerase lambda-3 2.7.7.48 0.660
1nmd ATPMajor actin / 0.660
1wet GUNHTH-type transcriptional repressor PurR / 0.660
1xxj UNCUricase 1.7.3.3 0.660
2d09 FLVBiflaviolin synthase CYP158A2 / 0.660
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.660
2jey HLOAcetylcholinesterase 3.1.1.7 0.660
2oap ANPType II secretion system protein (GspE-2) / 0.660
3f8p NADNADH oxidase/thioredoxin reductase / 0.660
3f8r NAPNADH oxidase/thioredoxin reductase / 0.660
3u9d ATPActin, alpha skeletal muscle / 0.660
3ypi PGHTriosephosphate isomerase 5.3.1.1 0.660
3zzn ADPL-lactate dehydrogenase / 0.660
4e5l DBHPolymerase acidic protein / 0.660
4j0p 1H8Beta-secretase 1 3.4.23.46 0.660
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.659
4cdg ADPBloom syndrome protein 3.6.4.12 0.659
4lc7 1WPBeta-secretase 1 3.4.23.46 0.659
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.658
1fp6 ADPNitrogenase iron protein 1 1.18.6.1 0.657
4j17 1HQBeta-secretase 1 3.4.23.46 0.655
4frs 0V6Beta-secretase 1 3.4.23.46 0.650