Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4h5c YS4 Farnesyl pyrophosphate synthase 2.5.1.10

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4h5c YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.273
4h5d YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.256
4dem YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.241
4lfv YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.239
4h5e YS4Farnesyl pyrophosphate synthase 2.5.1.10 1.233
4ga3 4GAFarnesyl pyrophosphate synthase 2.5.1.10 0.982
4l2x YL2Farnesyl pyrophosphate synthase 2.5.1.10 0.975
2f94 BFQFarnesyl pyrophosphate synthase 2.5.1.10 0.951
4dxj 0M9Farnesyl pyrophosphate synthase / 0.939
4q23 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.910
1yv5 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.909
3icz PB6Farnesyl pyrophosphate synthase / 0.909
1rqj RISFarnesyl diphosphate synthase 2.5.1.10 0.903
4kqs RISFarnesyl pyrophosphate synthase 2.5.1.10 0.902
4nke RISFarnesyl pyrophosphate synthase 2.5.1.10 0.889
4dwb 0M7Farnesyl pyrophosphate synthase / 0.886
3egt 722Farnesyl pyrophosphate synthase / 0.879
3rye UNRFarnesyl pyrophosphate synthase 2.5.1.10 0.876
3ez3 ZOLFarnesyl pyrophosphate synthase, putative / 0.844
3dyh 721Farnesyl pyrophosphate synthase / 0.841
1zw5 ZOLFarnesyl pyrophosphate synthase 2.5.1.10 0.821
3ldw ZOLFarnesyl pyrophosphate synthase, putative / 0.816
1yq7 RISFarnesyl pyrophosphate synthase 2.5.1.10 0.786
2o1o RISPutative farnesyl pyrophosphate synthase / 0.780
2zev B71Geranylgeranyl pyrophosphate synthase / 0.723
1khe GCPPhosphoenolpyruvate carboxykinase, cytosolic [GTP] 4.1.1.32 0.719
2z4y 252Geranylgeranyl pyrophosphate synthase / 0.717
5erm 210Fusicoccadiene synthase 4.2.3.43 0.716
2z4w 749Geranylgeranyl pyrophosphate synthase / 0.705
1svm ATPLarge T antigen 3.6.4 0.690
2nom DUTPoly(A) polymerase, putative / 0.687
3krf DSTGeranyl diphosphate synthase large subunit / 0.686
4brd ANPEctonucleoside triphosphate diphosphohydrolase I / 0.668
1lot ATPActin, alpha skeletal muscle / 0.666
4brg GNPEctonucleoside triphosphate diphosphohydrolase I / 0.666
4bri UNPEctonucleoside triphosphate diphosphohydrolase I / 0.666
1xtr GNPGTP-binding protein Rheb / 0.657
2e95 B75Geranylgeranyl pyrophosphate synthase / 0.657
3ori AGSSerine/threonine protein kinase / 0.657
4jvj 1MVFarnesyl pyrophosphate synthase 2.5.1.10 0.657
1rfq ATPActin, alpha skeletal muscle / 0.656
2yww ATPAspartate carbamoyltransferase regulatory chain / 0.656
2jlr ANPGenome polyprotein 3.4.21.91 0.655
4qg1 DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD1 3.1.5 0.655
2e8w IPEGeranylgeranyl pyrophosphate synthase / 0.654
2x0q ATPAlcaligin biosynthesis protein / 0.654
3mle ADPATP-dependent dethiobiotin synthetase BioD 6.3.3.3 0.654
5ero 210Fusicoccadiene synthase 2.5.1.29 0.654
3q5d GDPAtlastin-1 3.6.5 0.653
3ryw K9HFarnesyl pyrophosphate synthase, putative / 0.651
4hdo GNPRas-related protein Rap-1b / 0.650