Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4h3g 10Q Beta-secretase 1 3.4.23.46

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4h3g 10QBeta-secretase 1 3.4.23.46 0.929
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
4h3i 10VBeta-secretase 1 3.4.23.46 0.731
4h3j 10WBeta-secretase 1 3.4.23.46 0.724
4h3f 10OBeta-secretase 1 3.4.23.46 0.705
4h1e 10JBeta-secretase 1 3.4.23.46 0.688
4lc7 1WPBeta-secretase 1 3.4.23.46 0.664
4e5f 0N7Polymerase acidic protein / 0.660
2ohu IP7Beta-secretase 1 3.4.23.46 0.656