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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fuf 8UP Urokinase-type plasminogen activator 3.4.21.73

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fuf 8UPUrokinase-type plasminogen activator 3.4.21.73 0.959
4fui UI3Urokinase-type plasminogen activator 3.4.21.73 0.861
1sqt UI3Urokinase-type plasminogen activator 3.4.21.73 0.843
4fub 4UPUrokinase-type plasminogen activator 3.4.21.73 0.802
1u6q 745Urokinase-type plasminogen activator 3.4.21.73 0.797
4fud 6UPUrokinase-type plasminogen activator 3.4.21.73 0.789
4fuj 1U9Urokinase-type plasminogen activator 3.4.21.73 0.789
1owd 497Urokinase-type plasminogen activator 3.4.21.73 0.783
1vja 7INUrokinase-type plasminogen activator 3.4.21.73 0.775
1owe 675Urokinase-type plasminogen activator 3.4.21.73 0.773
4fue 7UPUrokinase-type plasminogen activator 3.4.21.73 0.770
1owk 303Urokinase-type plasminogen activator 3.4.21.73 0.767
1zsk 421Coagulation factor XI 3.4.21.27 0.720
1o5g CR9Prothrombin 3.4.21.5 0.714
3v0x ANHCationic trypsin 3.4.21.4 0.711
1ghv 120Prothrombin 3.4.21.5 0.697
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 0.692
4e7r 0NWProthrombin 3.4.21.5 0.687
2znk 31UProthrombin 3.4.21.5 0.674
3plp BBACationic trypsin 3.4.21.4 0.666
1drt PCVClavaminate synthase 1 1.14.11.21 0.660