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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ft4 SAH DNA (cytosine-5)-methyltransferase 1 2.1.1.37

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ft4 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.930
3ldg SAHUncharacterized protein / 0.700
4dmg SAMUncharacterized protein / 0.688
4rtm SAMDNA adenine methylase 2.1.1.72 0.673
4fp9 SAM5-methylcytosine rRNA methyltransferase NSUN4 2.1.1 0.669
2yx1 SFGtRNA (guanine(37)-N1)-methyltransferase Trm5b 2.1.1.228 0.667
10mh SAHModification methylase HhaI 2.1.1.37 0.662
3c3y SAHO-methyltransferase / 0.657
3pt6 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.656
3bgi SAHThiopurine S-methyltransferase 2.1.1.67 0.655
2zzn SAMtRNA (guanine(37)-N1)-methyltransferase Trm5b 2.1.1.228 0.651
4dcm SAMRibosomal RNA large subunit methyltransferase G 2.1.1.174 0.651
1g60 SAMModification methylase MboII 2.1.1.72 0.650
4rto SFGDNA adenine methylase 2.1.1.72 0.650