Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fpy 0V8 Sialidase B 3.2.1.18

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fpy 0V8Sialidase B 3.2.1.18 1.034
1dhi MTXDihydrofolate reductase 1.5.1.3 0.669
2b5v NAPGlucose 1-dehydrogenase / 0.661
5iot UMPFlavin-dependent thymidylate synthase 2.1.1.148 0.656
2zjm F1MBeta-secretase 1 3.4.23.46 0.655
4i6a HMG3-hydroxy-3-methylglutaryl-coenzyme A reductase 1.1.1.88 0.654