Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fl3 ANP Tyrosine-protein kinase SYK 2.7.10.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fl3 ANPTyrosine-protein kinase SYK 2.7.10.2 1.035
4fl2 ANPTyrosine-protein kinase SYK 2.7.10.2 0.974
5cno ANPEpidermal growth factor receptor 2.7.10.1 0.802
2gs7 ANPEpidermal growth factor receptor 2.7.10.1 0.775
4zse ANPEpidermal growth factor receptor 2.7.10.1 0.766
5cnn ANPEpidermal growth factor receptor 2.7.10.1 0.761
2vwi ANPSerine/threonine-protein kinase OSR1 2.7.11.1 0.712
3dqw AGSProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.709
2ozo ANPTyrosine-protein kinase ZAP-70 2.7.10.2 0.705
4bl1 ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.704
4otp ADPSerine/threonine-protein kinase RIO1 2.7.11.1 0.704
1b38 ATPCyclin-dependent kinase 2 2.7.11.22 0.698
1zp9 ATPRIO-type serine/threonine-protein kinase Rio1 2.7.11.1 0.696
1hck ATPCyclin-dependent kinase 2 2.7.11.22 0.693
3nyn SGVG protein-coupled receptor kinase 6 2.7.11.16 0.693
3lmg ANPReceptor tyrosine-protein kinase erbB-3 2.7.10.1 0.690
3vjo ANPEpidermal growth factor receptor 2.7.10.1 0.686
2b9f ADPMitogen-activated protein kinase FUS3 2.7.11.24 0.685
4aqk ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.684
3llt ANPProtein serine/threonine kinase-1 / 0.678
4iay ADPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.677
2pyw ADPMethylthioribose kinase 2.7.1.100 0.675
4bfm ANPMaternal embryonic leucine zipper kinase 2.7.11.1 0.675
4q5j ANPProtein BRASSINOSTEROID INSENSITIVE 1 2.7.10.1 0.675
4ux9 ANPMitogen-activated protein kinase 8 2.7.11.24 0.675
3ork AGSSerine/threonine protein kinase / 0.674
4lv7 ADPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.674
1jkl ANPDeath-associated protein kinase 1 2.7.11.1 0.672
3hrc ATP3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.669
3igo ANPCalmodulin-domain protein kinase 1, putative / 0.667
1tqp ATPRIO-type serine/threonine-protein kinase Rio2 2.7.11.1 0.666
2itn ANPEpidermal growth factor receptor 2.7.10.1 0.666
3ort AGSSerine/threonine protein kinase / 0.666
3rep ATPIntegrin-linked protein kinase 2.7.11.1 0.666
4ckj ADNProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.665
1q97 ATPSerine/threonine-protein kinase SKY1 2.7.11.1 0.663
2vnw M01cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.661
4lrj ANPUncharacterized protein / 0.661
2olc ADPMethylthioribose kinase 2.7.1.100 0.660
3gu4 ANPDeath-associated protein kinase 1 2.7.11.1 0.660
4bix ADPSensor histidine kinase CpxA / 0.660
4ifc ADPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.660
4riy ANPReceptor tyrosine-protein kinase erbB-3 2.7.10.1 0.660
4iir ANPSerine/threonine-protein kinase PRP4 homolog 2.7.11.1 0.659
2pup ADPMethylthioribose kinase 2.7.1.100 0.658
3g51 ANPRibosomal protein S6 kinase alpha-3 2.7.11.1 0.658
2pml ANPUncharacterized protein / 0.657
2xuu ADPDeath-associated protein kinase 1 2.7.11.1 0.656
3juh ANPCasein kinase II subunit alpha 2.7.11.1 0.656
2itv ANPEpidermal growth factor receptor 2.7.10.1 0.655
3dfc ANPDeath-associated protein kinase 1 2.7.11.1 0.654
3gu6 ADPDeath-associated protein kinase 1 2.7.11.1 0.654
1jkk ANPDeath-associated protein kinase 1 2.7.11.1 0.653
1tqm ANPRIO-type serine/threonine-protein kinase Rio2 2.7.11.1 0.653
2eva ADNMitogen-activated protein kinase kinase kinase 7 2.7.11.25 0.653
3sl2 ATPSensor histidine kinase WalK / 0.653
4fg8 ATPCalcium/calmodulin-dependent protein kinase type 1 2.7.11.17 0.653
4yhj AN2G protein-coupled receptor kinase 4 2.7.11.16 0.653
5itz GTPTubulin alpha-1B chain / 0.652
1ad5 ANPTyrosine-protein kinase HCK 2.7.10.2 0.651
2xan ANPInositol-pentakisphosphate 2-kinase 2.7.1.158 0.651
4ic7 ANPMitogen-activated protein kinase 7 2.7.11.24 0.651
4xw4 ANPcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
2pui ADPMethylthioribose kinase 2.7.1.100 0.650
3agl A03cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.650
4c3r ACPAurora kinase A 2.7.11.1 0.650