Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fkt 48K Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fkt 48KCyclin-dependent kinase 2 2.7.11.22 0.993
4fks 46KCyclin-dependent kinase 2 2.7.11.22 0.941
4fkv 61KCyclin-dependent kinase 2 2.7.11.22 0.929
4fkp LS5Cyclin-dependent kinase 2 2.7.11.22 0.918
1ke5 LS1Cyclin-dependent kinase 2 2.7.11.22 0.917
4fkw 62KCyclin-dependent kinase 2 2.7.11.22 0.886
1ke9 LS5Cyclin-dependent kinase 2 2.7.11.22 0.874
1ke8 LS4Cyclin-dependent kinase 2 2.7.11.22 0.871
4fkr 45KCyclin-dependent kinase 2 2.7.11.22 0.865
1ke6 LS2Cyclin-dependent kinase 2 2.7.11.22 0.863
1ke7 LS3Cyclin-dependent kinase 2 2.7.11.22 0.853
1fvv 107Cyclin-dependent kinase 2 2.7.11.22 0.844
4fkq 42KCyclin-dependent kinase 2 2.7.11.22 0.827
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.825
1fvt 106Cyclin-dependent kinase 2 2.7.11.22 0.813
4fx3 60KCyclin-dependent kinase 2 2.7.11.22 0.801
1p2a 5BNCyclin-dependent kinase 2 2.7.11.22 0.775
3ti1 B49Cyclin-dependent kinase 2 2.7.11.22 0.773
4acm 7YGCyclin-dependent kinase 2 2.7.11.22 0.745
3mtl FEFCyclin-dependent kinase 16 2.7.11.22 0.743
3py0 SU9Cyclin-dependent kinase 2 2.7.11.22 0.739
1v0o INRCell division control protein 2 homolog 2.7.11.22 0.736
3eb0 DRKUncharacterized protein / 0.730
1q41 IXMGlycogen synthase kinase-3 beta 2.7.11.26 0.728
2bhe BRYCyclin-dependent kinase 2 2.7.11.22 0.728
2b55 D31Cyclin-dependent kinase 2 2.7.11.22 0.716
1e9h INRCyclin-dependent kinase 2 2.7.11.22 0.714
1uv5 BRWGlycogen synthase kinase-3 beta 2.7.11.26 0.713
2w06 FRVCyclin-dependent kinase 2 2.7.11.22 0.699
3ezr EZRCyclin-dependent kinase 2 2.7.11.22 0.694
1y8y CT7Cyclin-dependent kinase 2 2.7.11.22 0.691
3tiz 3TICyclin-dependent kinase 2 2.7.11.22 0.690
2vtn LZ7Cyclin-dependent kinase 2 2.7.11.22 0.687
3pj8 404Cyclin-dependent kinase 2 2.7.11.22 0.687
3qrt X14Cyclin-dependent kinase 2 2.7.11.22 0.685
2x2l X2LProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.680
3qx2 X63Cyclin-dependent kinase 2 2.7.11.22 0.680
2r3m SCXCyclin-dependent kinase 2 2.7.11.22 0.676
3r73 X87Cyclin-dependent kinase 2 2.7.11.22 0.675
3r7e X88Cyclin-dependent kinase 2 2.7.11.22 0.674
2qkr IXMCdc2-like CDK2/CDC28 like protein kinase / 0.673
2wxv WXVCyclin-dependent kinase 2 2.7.11.22 0.672
1gii 1PUCyclin-dependent kinase 2 2.7.11.22 0.671
3r1s X73Cyclin-dependent kinase 2 2.7.11.22 0.671
4bgh 3I6Cyclin-dependent kinase 2 2.7.11.22 0.671
3qxo X65Cyclin-dependent kinase 2 2.7.11.22 0.670
3r6x X84Cyclin-dependent kinase 2 2.7.11.22 0.670
3r7v Z02Cyclin-dependent kinase 2 2.7.11.22 0.670
2vz6 FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha 2.7.11.17 0.669
3rm7 19ZCyclin-dependent kinase 2 2.7.11.22 0.669
1qpj STUTyrosine-protein kinase Lck 2.7.10.2 0.668
2vtj LZ4Cyclin-dependent kinase 2 2.7.11.22 0.668
3qwk X62Cyclin-dependent kinase 2 2.7.11.22 0.668
3rpo 24ZCyclin-dependent kinase 2 2.7.11.22 0.666
2c6o 4SPCyclin-dependent kinase 2 2.7.11.22 0.665
2xmy CDKCyclin-dependent kinase 2 2.7.11.22 0.663
3ezv EZVCyclin-dependent kinase 2 2.7.11.22 0.663
3r83 Z14Cyclin-dependent kinase 2 2.7.11.22 0.662
3rpv 26ZCyclin-dependent kinase 2 2.7.11.22 0.662
4fsm HK1Serine/threonine-protein kinase Chk1 2.7.11.1 0.662
3rai X85Cyclin-dependent kinase 2 2.7.11.22 0.661
4aw5 30KEphrin type-B receptor 4 2.7.10.1 0.661
3r1y X76Cyclin-dependent kinase 2 2.7.11.22 0.660
3say OFTGlycogen synthase kinase-3 beta 2.7.11.26 0.660
4fsn A58Serine/threonine-protein kinase Chk1 2.7.11.1 0.660
3lfs A07Cyclin-dependent kinase 2 2.7.11.22 0.659
4qmp DKISerine/threonine-protein kinase 24 2.7.11.1 0.659
1urw I1PCyclin-dependent kinase 2 2.7.11.22 0.658
3lfq A28Cyclin-dependent kinase 2 2.7.11.22 0.658
3qqf X07Cyclin-dependent kinase 2 2.7.11.22 0.657
1ckp PVBCyclin-dependent kinase 2 2.7.11.22 0.656
1pxl CK4Cyclin-dependent kinase 2 2.7.11.22 0.656
2wip P49Cyclin-dependent kinase 2 2.7.11.22 0.656
4fsu HK5Serine/threonine-protein kinase Chk1 2.7.11.1 0.655
2p33 J07Mitogen-activated protein kinase 10 2.7.11.24 0.654
2r3q 5SCCyclin-dependent kinase 2 2.7.11.22 0.654
3g0e B49Mast/stem cell growth factor receptor Kit 2.7.10.1 0.654
3o0g 3O0Cyclin-dependent-like kinase 5 2.7.11.1 0.654
4fto 3HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.654
5ap7 SVEDual specificity protein kinase TTK 2.7.12.1 0.654
1gih 1PUCyclin-dependent kinase 2 2.7.11.22 0.653
1dm2 HMDCyclin-dependent kinase 2 2.7.11.22 0.652
2euf LQQCyclin-dependent kinase 6 2.7.11.22 0.651
2gnl H52cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
3rk5 07ZCyclin-dependent kinase 2 2.7.11.22 0.651
4grb 0XGCasein kinase II subunit alpha 2.7.11.1 0.650