Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fkp LS5 Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fkp LS5Cyclin-dependent kinase 2 2.7.11.22 1.031
1ke5 LS1Cyclin-dependent kinase 2 2.7.11.22 0.936
1ke8 LS4Cyclin-dependent kinase 2 2.7.11.22 0.931
4fkt 48KCyclin-dependent kinase 2 2.7.11.22 0.918
4fks 46KCyclin-dependent kinase 2 2.7.11.22 0.905
4fkv 61KCyclin-dependent kinase 2 2.7.11.22 0.883
2vti LZ3Cyclin-dependent kinase 2 2.7.11.22 0.860
1ke6 LS2Cyclin-dependent kinase 2 2.7.11.22 0.852
1fvt 106Cyclin-dependent kinase 2 2.7.11.22 0.843
4fkq 42KCyclin-dependent kinase 2 2.7.11.22 0.843
4fkw 62KCyclin-dependent kinase 2 2.7.11.22 0.842
3ti1 B49Cyclin-dependent kinase 2 2.7.11.22 0.804
1q41 IXMGlycogen synthase kinase-3 beta 2.7.11.26 0.799
1ke7 LS3Cyclin-dependent kinase 2 2.7.11.22 0.795
1fvv 107Cyclin-dependent kinase 2 2.7.11.22 0.781
1ke9 LS5Cyclin-dependent kinase 2 2.7.11.22 0.781
3py0 SU9Cyclin-dependent kinase 2 2.7.11.22 0.771
4fkr 45KCyclin-dependent kinase 2 2.7.11.22 0.762
1uv5 BRWGlycogen synthase kinase-3 beta 2.7.11.26 0.749
3eb0 DRKUncharacterized protein / 0.732
3mtl FEFCyclin-dependent kinase 16 2.7.11.22 0.731
1e9h INRCyclin-dependent kinase 2 2.7.11.22 0.728
4fkg 4CKCyclin-dependent kinase 2 2.7.11.22 0.724
3ezr EZRCyclin-dependent kinase 2 2.7.11.22 0.722
4acm 7YGCyclin-dependent kinase 2 2.7.11.22 0.720
1y91 CT9Cyclin-dependent kinase 2 2.7.11.22 0.715
1y8y CT7Cyclin-dependent kinase 2 2.7.11.22 0.713
3ezv EZVCyclin-dependent kinase 2 2.7.11.22 0.705
3l9l L9LcAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.705
3r9d X6BCyclin-dependent kinase 2 2.7.11.22 0.698
1gih 1PUCyclin-dependent kinase 2 2.7.11.22 0.696
2qkr IXMCdc2-like CDK2/CDC28 like protein kinase / 0.695
1gii 1PUCyclin-dependent kinase 2 2.7.11.22 0.693
3qrt X14Cyclin-dependent kinase 2 2.7.11.22 0.691
4fx3 60KCyclin-dependent kinase 2 2.7.11.22 0.690
3qtz X42Cyclin-dependent kinase 2 2.7.11.22 0.689
2w06 FRVCyclin-dependent kinase 2 2.7.11.22 0.687
2vz6 FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha 2.7.11.17 0.684
2b55 D31Cyclin-dependent kinase 2 2.7.11.22 0.683
2b52 D42Cyclin-dependent kinase 2 2.7.11.22 0.682
4lyn 1YGCyclin-dependent kinase 2 2.7.11.22 0.682
3r8p Z46Cyclin-dependent kinase 2 2.7.11.22 0.680
3rpy 27ZCyclin-dependent kinase 2 2.7.11.22 0.679
4bgh 3I6Cyclin-dependent kinase 2 2.7.11.22 0.679
2c6m DT5Cyclin-dependent kinase 2 2.7.11.22 0.673
1dm2 HMDCyclin-dependent kinase 2 2.7.11.22 0.672
2vtj LZ4Cyclin-dependent kinase 2 2.7.11.22 0.668
2r3m SCXCyclin-dependent kinase 2 2.7.11.22 0.667
4qmz B49Serine/threonine-protein kinase 24 2.7.11.1 0.667
1urw I1PCyclin-dependent kinase 2 2.7.11.22 0.666
4ftn 2HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.665
2c6o 4SPCyclin-dependent kinase 2 2.7.11.22 0.664
4ftl H0KSerine/threonine-protein kinase Chk1 2.7.11.1 0.662
1v0o INRCell division control protein 2 homolog 2.7.11.22 0.660
5e8w STUTGF-beta receptor type-1 2.7.11.30 0.660
3bgq VX2Serine/threonine-protein kinase pim-1 2.7.11.1 0.657
2bhe BRYCyclin-dependent kinase 2 2.7.11.22 0.656
4fki 09KCyclin-dependent kinase 2 2.7.11.22 0.656
4fsq HK3Serine/threonine-protein kinase Chk1 2.7.11.1 0.656
3r9h Z67Cyclin-dependent kinase 2 2.7.11.22 0.655
3lfq A28Cyclin-dependent kinase 2 2.7.11.22 0.654
3sqq 99ZCyclin-dependent kinase 2 2.7.11.22 0.653
4fto 3HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.653
2jdv L20cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.651
3qxp X64Cyclin-dependent kinase 2 2.7.11.22 0.651
3rpo 24ZCyclin-dependent kinase 2 2.7.11.22 0.651
1qpj STUTyrosine-protein kinase Lck 2.7.10.2 0.650
2b54 D05Cyclin-dependent kinase 2 2.7.11.22 0.650
2x2k X2KProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.650