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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fk6 0UJ Tyrosine-protein kinase JAK1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fk6 0UJTyrosine-protein kinase JAK1 / 0.966
4e5w 0NTTyrosine-protein kinase JAK1 / 0.722
4e4n 0NLTyrosine-protein kinase JAK1 / 0.699
4e6q 0NVTyrosine-protein kinase JAK2 / 0.695
4ivb 1J5Tyrosine-protein kinase JAK1 / 0.695
4ei4 0Q2Tyrosine-protein kinase JAK1 / 0.666
4f08 1RSTyrosine-protein kinase JAK2 / 0.656
4f09 JAKTyrosine-protein kinase JAK2 / 0.656
2clq STUMitogen-activated protein kinase kinase kinase 5 2.7.11.25 0.651