Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4fgg 0U5 Dihydrofolate reductase 1.5.1.3

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4fgg 0U5Dihydrofolate reductase 1.5.1.3 1.408
4fgh 0U6Dihydrofolate reductase 1.5.1.3 1.157
3m09 RARDihydrofolate reductase 1.5.1.3 1.002
3m08 RARDihydrofolate reductase 1.5.1.3 0.959
3fre TOPDihydrofolate reductase 1.5.1.3 0.849
4elf 35IDihydrofolate reductase / 0.834
3fl8 RARDihydrofolate reductase / 0.814
4ele 31IDihydrofolate reductase / 0.716
4elb 34SDihydrofolate reductase / 0.714
3sqy Q11Dihydrofolate reductase 1.5.1.3 0.681
4elg 52JDihydrofolate reductase / 0.673
3fy9 XCFDihydrofolate reductase 1.5.1.3 0.672
2w9h TOPDihydrofolate reductase 1.5.1.3 0.658
4p68 MTXDihydrofolate reductase / 0.655
3jw5 TOPDihydrofolate reductase / 0.653