Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4f65 0S9 Fibroblast growth factor receptor 1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4f65 0S9Fibroblast growth factor receptor 1 / 1.075
4nks 2M2Fibroblast growth factor receptor 1 / 0.787
4f64 0S8Fibroblast growth factor receptor 1 / 0.778
4nk9 2K5Fibroblast growth factor receptor 1 / 0.768
4aoj V4ZHigh affinity nerve growth factor receptor 2.7.10.1 0.705
3w16 P9JAurora kinase A 2.7.11.1 0.704
4agc AXIVascular endothelial growth factor receptor 2 2.7.10.1 0.703
4f63 0S7Fibroblast growth factor receptor 1 / 0.702
4xli 1N1Abelson tyrosine-protein kinase 2 2.7.10.2 0.695
2xa4 AZ5Tyrosine-protein kinase JAK2 / 0.692
3ggf GVDSerine/threonine-protein kinase 26 / 0.688
4fsm HK1Serine/threonine-protein kinase Chk1 2.7.11.1 0.684
4nka 2K7Fibroblast growth factor receptor 1 / 0.681
2qhn 582Serine/threonine-protein kinase Chk1 2.7.11.1 0.679
1vyw 292Cyclin-dependent kinase 2 2.7.11.22 0.673
2jc6 QPPCalcium/calmodulin-dependent protein kinase type 1D 2.7.11.17 0.673
4c61 LMMTyrosine-protein kinase JAK2 / 0.673
3oct 1N1Tyrosine-protein kinase BTK 2.7.10.2 0.671
3i81 EBIInsulin-like growth factor 1 receptor 2.7.10.1 0.662
2j4z 626Aurora kinase A 2.7.11.1 0.659
2zva 1N1Tyrosine-protein kinase Lyn 2.7.10.2 0.659
2c3k ABOSerine/threonine-protein kinase Chk1 2.7.11.1 0.657
4ftq 4HKSerine/threonine-protein kinase Chk1 2.7.11.1 0.657
4o0r X4ZSerine/threonine-protein kinase PAK 1 2.7.11.1 0.656
5amn DTQProto-oncogene tyrosine-protein kinase receptor Ret 2.7.10.1 0.656
3qlg 1N1Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.655
4ase AV9Vascular endothelial growth factor receptor 2 2.7.10.1 0.654
2fgi PD1Fibroblast growth factor receptor 1 / 0.652
4fkj 11KCyclin-dependent kinase 2 2.7.11.22 0.652
2bdj HETProto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.650