Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4eor 4SP Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4eor 4SPCyclin-dependent kinase 2 2.7.11.22 0.928
2iw8 4SPCyclin-dependent kinase 2 2.7.11.22 0.897
1h1s 4SPCyclin-dependent kinase 2 2.7.11.22 0.851
2iw9 4SPCyclin-dependent kinase 2 2.7.11.22 0.834
1oiu N76Cyclin-dependent kinase 2 2.7.11.22 0.815
1oi9 N20Cyclin-dependent kinase 2 2.7.11.22 0.784
1oiy N41Cyclin-dependent kinase 2 2.7.11.22 0.750
3r9d X6BCyclin-dependent kinase 2 2.7.11.22 0.728
3rpy 27ZCyclin-dependent kinase 2 2.7.11.22 0.718
4eok 4SPCyclin-dependent kinase 2 2.7.11.22 0.718
1h1r 6CPCyclin-dependent kinase 2 2.7.11.22 0.706
1h1q 2A6Cyclin-dependent kinase 2 2.7.11.22 0.696
2c6o 4SPCyclin-dependent kinase 2 2.7.11.22 0.689
2wxv WXVCyclin-dependent kinase 2 2.7.11.22 0.674
1ogu ST8Cyclin-dependent kinase 2 2.7.11.22 0.673
4ez3 0S0Cyclin-dependent kinase 2 2.7.11.22 0.670
4bgh 3I6Cyclin-dependent kinase 2 2.7.11.22 0.664
3qu0 X40Cyclin-dependent kinase 2 2.7.11.22 0.661
1oit HDTCyclin-dependent kinase 2 2.7.11.22 0.660
4aot GW8Serine/threonine-protein kinase 10 2.7.11.1 0.652