Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4eki 0QK Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4eki 0QKHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 1.188
4ekg 0QJHistone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.862
4er7 AW3Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.797
4er6 AW2Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.741
2yvl SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.700
4yac NAIC alpha-dehydrogenase / 0.700
1orr NADCDP-paratose 2-epimerase / 0.688
5bxy SAHPutative RNA methylase family UPF0020 / 0.687
5eku SAHArginine N-methyltransferase, putative / 0.678
1i9g SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.673
1y9d FADPyruvate oxidase 1.2.3.3 0.671
3grr SAHProbable ribosomal RNA small subunit methyltransferase A / 0.668
5ccb SAHtRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A 2.1.1.220 0.665
1v59 NADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.663
2nyu SAMrRNA methyltransferase 2, mitochondrial / 0.660
1skm SAHModification methylase HhaI 2.1.1.37 0.659
1l3i SAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) / 0.658
1zmc NADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.656
3a27 SAMtRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase / 0.656
2c31 ADPOxalyl-CoA decarboxylase 4.1.1.8 0.655
4ek9 EP4Histone-lysine N-methyltransferase, H3 lysine-79 specific 2.1.1.43 0.654
3lga SAHtRNA (adenine(57)-N(1)/adenine(58)-N(1))-methyltransferase TrmI 2.1.1.219 0.653
4m37 SAHProtein arginine N-methyltransferase 7 2.1.1 0.651