Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ek8 16K Cyclin-dependent kinase 2 2.7.11.22

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ek8 16KCyclin-dependent kinase 2 2.7.11.22 0.908
3sw7 19KCyclin-dependent kinase 2 2.7.11.22 0.762
2c5y MTWCyclin-dependent kinase 2 2.7.11.22 0.761
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
3sw4 18KCyclin-dependent kinase 2 2.7.11.22 0.734
1pxm CK5Cyclin-dependent kinase 2 2.7.11.22 0.732
2xnb Y8LCyclin-dependent kinase 2 2.7.11.22 0.704
1pxp CK8Cyclin-dependent kinase 2 2.7.11.22 0.695
1pxo CK7Cyclin-dependent kinase 2 2.7.11.22 0.693
1urw I1PCyclin-dependent kinase 2 2.7.11.22 0.681
3qzg X67Cyclin-dependent kinase 2 2.7.11.22 0.681
2w06 FRVCyclin-dependent kinase 2 2.7.11.22 0.667
2wih P48Cyclin-dependent kinase 2 2.7.11.22 0.662
1pxl CK4Cyclin-dependent kinase 2 2.7.11.22 0.661
4e5f 0N7Polymerase acidic protein / 0.660
1pxk CK3Cyclin-dependent kinase 2 2.7.11.22 0.659
3tiz 3TICyclin-dependent kinase 2 2.7.11.22 0.657
2r64 740Cyclin-dependent kinase 2 2.7.11.22 0.656
1oir HDYCyclin-dependent kinase 2 2.7.11.22 0.652
2wxv WXVCyclin-dependent kinase 2 2.7.11.22 0.650
2x4f 16XMyosin light chain kinase family member 4 2.7.11.1 0.650