sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4ehu | ANP | 2-hydroxyisocaproyl-CoA dehydratase activator |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 4ehu | ANP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 1.224 | |
| 4a62 | ANP | Plasmid segregation protein ParM | / | 0.968 | |
| 4eht | ADP | 2-hydroxyisocaproyl-CoA dehydratase activator | / | 0.901 | |
| 1kxp | ATP | Actin, alpha skeletal muscle | / | 0.889 | |
| 2q36 | ATP | Actin, alpha skeletal muscle | / | 0.858 | |
| 4pki | ATP | Actin, alpha skeletal muscle | / | 0.834 | |
| 3m1f | ATP | Actin, alpha skeletal muscle | / | 0.833 | |
| 4brg | GNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.829 | |
| 1eqy | ATP | Actin, alpha skeletal muscle | / | 0.826 | |
| 2v51 | ATP | Actin, alpha skeletal muscle | / | 0.826 | |
| 1c0f | ATP | Major actin | / | 0.821 | |
| 2a41 | ATP | Actin, alpha skeletal muscle | / | 0.820 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.819 | |
| 3a5m | ATP | Major actin | / | 0.814 | |
| 1qz5 | ATP | Actin, alpha skeletal muscle | / | 0.810 | |
| 4b1v | ATP | Actin, alpha skeletal muscle | / | 0.810 | |
| 4pkg | ATP | Actin, alpha skeletal muscle | / | 0.810 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.806 | |
| 1wua | ATP | Actin, alpha skeletal muscle | / | 0.803 | |
| 1t44 | ATP | Actin, alpha skeletal muscle | / | 0.799 | |
| 2fsn | ADP | Archaeal actin homolog | / | 0.798 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.798 | |
| 4k41 | ATP | Actin, alpha skeletal muscle | / | 0.795 | |
| 3daw | ATP | Actin, alpha skeletal muscle | / | 0.793 | |
| 5ce3 | ATP | Actin | / | 0.790 | |
| 1nlv | ATP | Major actin | / | 0.789 | |
| 1yxq | ATP | Actin, alpha skeletal muscle | / | 0.788 | |
| 2zgy | GDP | Plasmid segregation protein ParM | / | 0.779 | |
| 3ffk | ATP | Actin, alpha skeletal muscle | / | 0.779 | |
| 3mn6 | ATP | Actin-5C | / | 0.779 | |
| 3m6g | ATP | Actin, alpha skeletal muscle | / | 0.775 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.774 | |
| 4pl8 | ATP | Actin, alpha skeletal muscle | / | 0.774 | |
| 1dej | ATP | Major actin | / | 0.772 | |
| 4pkh | ADP | Actin, alpha skeletal muscle | / | 0.771 | |
| 3a5o | ATP | Major actin | / | 0.768 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.766 | |
| 3wt0 | ATP | Cell division protein FtsA | / | 0.763 | |
| 4cbx | ATP | Actin-2 | / | 0.762 | |
| 3mn7 | ATP | Actin-5C | / | 0.759 | |
| 1mdu | ATP | Actin, alpha skeletal muscle | / | 0.758 | |
| 3w3d | ATP | Actin, gamma-enteric smooth muscle | / | 0.756 | |
| 1rfq | ATP | Actin, alpha skeletal muscle | / | 0.753 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.750 | |
| 4b9q | ATP | Chaperone protein DnaK | / | 0.749 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.748 | |
| 1lot | ATP | Actin, alpha skeletal muscle | / | 0.748 | |
| 4jhd | ANP | Actin-5C | / | 0.748 | |
| 2e2q | ADP | ATP-dependent hexokinase | / | 0.745 | |
| 3eks | ATP | Actin-5C | / | 0.743 | |
| 1rgi | ATP | Actin, alpha skeletal muscle | / | 0.742 | |
| 3chw | ATP | Major actin | / | 0.737 | |
| 3d2e | ATP | Heat shock protein homolog SSE1 | / | 0.734 | |
| 3eku | ATP | Actin-5C | / | 0.734 | |
| 2q97 | ATP | Actin, alpha skeletal muscle | / | 0.732 | |
| 1mwm | ADP | Plasmid segregation protein ParM | / | 0.727 | |
| 3mn9 | ATP | Actin-5C | / | 0.724 | |
| 3el2 | ATP | Actin-5C | / | 0.720 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.717 | |
| 3wqt | ANP | Cell division protein FtsA | / | 0.715 | |
| 2oan | ATP | Actin, cytoplasmic 1 | / | 0.709 | |
| 1ijj | ATP | Actin, alpha skeletal muscle | / | 0.698 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.691 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.690 | |
| 2d1s | SLU | Luciferin 4-monooxygenase | 1.13.12.7 | 0.688 | |
| 4ci6 | ATP | Actin | / | 0.683 | |
| 5f2r | ACP | 78 kDa glucose-regulated protein | / | 0.683 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.677 | |
| 2p9k | ATP | Actin-related protein 2 | / | 0.672 | |
| 4ej7 | ATP | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.671 | |
| 1ao0 | ADP | Amidophosphoribosyltransferase | / | 0.667 | |
| 4m63 | ATP | Actin-5C | / | 0.666 | |
| 2d0o | ADP | Diol dehydratase-reactivating factor alpha subunit | / | 0.662 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.659 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.656 | |
| 5bsm | ATP | 4-coumarate--CoA ligase 2 | 6.2.1.12 | 0.656 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.655 | |
| 4lfv | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.655 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.655 | |
| 4rwt | ANP | Actin-5C | / | 0.654 | |
| 4xjc | TTP | dCTP deaminase | / | 0.654 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.651 |