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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dij BLF E3 ubiquitin-protein ligase Mdm2 6.3.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
4dij BLFE3 ubiquitin-protein ligase Mdm2 6.3.2 1.056
1n35 CH1RNA-directed RNA polymerase lambda-3 2.7.7.48 0.744
1nmd ATPMajor actin / 0.744
2fzk CTPAspartate carbamoyltransferase regulatory chain / 0.744
2oap ANPType II secretion system protein (GspE-2) / 0.744
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.744
3cwq ADPParA family chromosome partitioning protein / 0.744
3f8r NAPNADH oxidase/thioredoxin reductase / 0.744
3fzf ATPHeat shock cognate 71 kDa protein / 0.744
3u9d ATPActin, alpha skeletal muscle / 0.744
3ypi PGHTriosephosphate isomerase 5.3.1.1 0.744
3zzn ADPL-lactate dehydrogenase / 0.744
5bnt NAPAspartate-semialdehyde dehydrogenase 1.2.1.11 0.744
4erf 0R3E3 ubiquitin-protein ligase Mdm2 6.3.2 0.705
4jwr 1MYE3 ubiquitin-protein ligase Mdm2 6.3.2 0.705
4jsc 1OYE3 ubiquitin-protein ligase Mdm2 6.3.2 0.699
4jrg I09E3 ubiquitin-protein ligase Mdm2 6.3.2 0.689
4ere 0R2E3 ubiquitin-protein ligase Mdm2 6.3.2 0.684
1rv1 IMZE3 ubiquitin-protein ligase Mdm2 6.3.2 0.683
1yra GDPGPN-loop GTPase PAB0955 / 0.660
2hru ADPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.660
2hs4 ACPPhosphoribosylformylglycinamidine synthase subunit PurL / 0.660
2lzg 13QE3 ubiquitin-protein ligase Mdm2 6.3.2 0.660
2xtn GTPGTPase IMAP family member 2 / 0.660
3fwy ADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein / 0.660
3kjg ADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC / 0.660
4cdg ADPBloom syndrome protein 3.6.4.12 0.660
4nxv GDPMitochondrial dynamics protein MID51 / 0.660
4o3m ADPBloom syndrome protein 3.6.4.12 0.660
4jvr 1MTE3 ubiquitin-protein ligase Mdm2 6.3.2 0.655