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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4deg 0JJ Hepatocyte growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
4deg 0JJHepatocyte growth factor receptor 2.7.10.1 0.924
3zbx 6XEHepatocyte growth factor receptor 2.7.10.1 0.684
4fny I3KALK tyrosine kinase receptor 2.7.10.1 0.680
3tub FPUTyrosine-protein kinase SYK 2.7.10.2 0.651
3zc5 W9ZHepatocyte growth factor receptor 2.7.10.1 0.650