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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4da4 SAH DNA (cytosine-5)-methyltransferase 1 2.1.1.37

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4da4 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.914
3pt9 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.730
4wxx SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.691
3pt6 SAHDNA (cytosine-5)-methyltransferase 1 2.1.1.37 0.664
2yvl SAMtRNA (adenine(58)-N(1))-methyltransferase TrmI / 0.657