Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4cd0 AWJ ALK tyrosine kinase receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4cd0 AWJALK tyrosine kinase receptor 2.7.10.1 1.108
4ccu AWFALK tyrosine kinase receptor 2.7.10.1 0.978
4ccb OFGALK tyrosine kinase receptor 2.7.10.1 0.925
5aaa VGHALK tyrosine kinase receptor 2.7.10.1 0.844
5aab VGHALK tyrosine kinase receptor 2.7.10.1 0.819
4anq VGHALK tyrosine kinase receptor 2.7.10.1 0.801
2xp2 VGHALK tyrosine kinase receptor 2.7.10.1 0.797
4ans VGHALK tyrosine kinase receptor 2.7.10.1 0.792
2yfx VGHALK tyrosine kinase receptor 2.7.10.1 0.790
5aac VGHALK tyrosine kinase receptor 2.7.10.1 0.782
2wtj WTJSerine/threonine-protein kinase Chk2 2.7.11.1 0.664
3bkb STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.656
3r8z Z63Cyclin-dependent kinase 2 2.7.11.22 0.655
5e8y STUTGF-beta receptor type-2 2.7.11.30 0.653
3a4o STUTyrosine-protein kinase Lyn 2.7.10.2 0.652