Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ccb OFG ALK tyrosine kinase receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ccb OFGALK tyrosine kinase receptor 2.7.10.1 1.003
4ccu AWFALK tyrosine kinase receptor 2.7.10.1 0.926
4cd0 AWJALK tyrosine kinase receptor 2.7.10.1 0.925
5aaa VGHALK tyrosine kinase receptor 2.7.10.1 0.903
5aab VGHALK tyrosine kinase receptor 2.7.10.1 0.875
2xp2 VGHALK tyrosine kinase receptor 2.7.10.1 0.847
4anq VGHALK tyrosine kinase receptor 2.7.10.1 0.829
4ans VGHALK tyrosine kinase receptor 2.7.10.1 0.818
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
2iw6 QQ2Cyclin-dependent kinase 2 2.7.11.22 0.672
2cgw 3C3Serine/threonine-protein kinase Chk1 2.7.11.1 0.670
3cd3 STUTyrosine-protein kinase Fes/Fps 2.7.10.2 0.667
2wtj WTJSerine/threonine-protein kinase Chk2 2.7.11.1 0.666
3zls 92PDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.664
2z7q ACPRibosomal protein S6 kinase alpha-1 2.7.11.1 0.663
2buj STUSerine/threonine-protein kinase 16 / 0.661
3rk5 07ZCyclin-dependent kinase 2 2.7.11.22 0.660
3qtu X44Cyclin-dependent kinase 2 2.7.11.22 0.659
4e4l 0NHTyrosine-protein kinase JAK1 / 0.655
3r8z Z63Cyclin-dependent kinase 2 2.7.11.22 0.654