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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4c4f 7CE Dual specificity protein kinase TTK 2.7.12.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4c4f 7CEDual specificity protein kinase TTK 2.7.12.1 0.862
4c4g 7RODual specificity protein kinase TTK 2.7.12.1 0.780
4c4i X20Dual specificity protein kinase TTK 2.7.12.1 0.771
4c4h 7RODual specificity protein kinase TTK 2.7.12.1 0.733
4c4j X21Dual specificity protein kinase TTK 2.7.12.1 0.728
5ap5 7RODual specificity protein kinase TTK 2.7.12.1 0.727
3she I85MAP kinase-activated protein kinase 3 2.7.11.1 0.686
4bi1 ZO6Dual specificity protein kinase TTK 2.7.12.1 0.655
5ap7 SVEDual specificity protein kinase TTK 2.7.12.1 0.655