Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4biz ADP Sensor histidine kinase CpxA

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4biz ADPSensor histidine kinase CpxA / 1.035
4bix ADPSensor histidine kinase CpxA / 0.754
2c2a ADPSensor histidine kinase / 0.748
3sl2 ATPSensor histidine kinase WalK / 0.716
1id0 ANPSensor protein PhoQ 2.7.13.3 0.693
1gjv AGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial 2.7.11.4 0.692
4pl9 ADPEthylene receptor 1 / 0.676
1kp2 ATPArgininosuccinate synthase 6.3.4.5 0.670
3dge ADPSensor histidine kinase / 0.670
3crl ANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial 2.7.11.2 0.665
1nhh ANPDNA mismatch repair protein MutL / 0.664
1i5a ACPChemotaxis protein CheA 2.7.13.3 0.659
1i58 ADPChemotaxis protein CheA 2.7.13.3 0.654
4prx ADPDNA gyrase subunit B / 0.654
2zkj ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial 2.7.11.2 0.653
3w2f NADNADH-cytochrome b5 reductase 3 1.6.2.2 0.652