Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4bdh WVI Serine/threonine-protein kinase Chk2 2.7.11.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4bdh WVISerine/threonine-protein kinase Chk2 2.7.11.1 0.798
1g7u PEP2-dehydro-3-deoxyphosphooctonate aldolase 2.5.1.55 0.744
4e5i 0N9Polymerase acidic protein / 0.744
2xa4 AZ5Tyrosine-protein kinase JAK2 / 0.688
3w16 P9JAurora kinase A 2.7.11.1 0.682
4bdf H3RSerine/threonine-protein kinase Chk2 2.7.11.1 0.681
1vyw 292Cyclin-dependent kinase 2 2.7.11.22 0.677
4f63 0S7Fibroblast growth factor receptor 1 / 0.676
4fkg 4CKCyclin-dependent kinase 2 2.7.11.22 0.672
4bdi HAUSerine/threonine-protein kinase Chk2 2.7.11.1 0.669
3nlb 5BESerine/threonine-protein kinase Chk1 2.7.11.1 0.665
4jbq VX6Aurora kinase A 2.7.11.1 0.665
2j4z 626Aurora kinase A 2.7.11.1 0.664
2xyn VX6Abelson tyrosine-protein kinase 2 2.7.10.2 0.664
4aoj V4ZHigh affinity nerve growth factor receptor 2.7.10.1 0.664
1vyz N5BCyclin-dependent kinase 2 2.7.11.22 0.662
4ek6 10KCyclin-dependent kinase 2 2.7.11.22 0.661
4f64 0S8Fibroblast growth factor receptor 1 / 0.661
3amb VX6cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.660
3e5a VX6Aurora kinase A 2.7.11.1 0.660
3zly YSODual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.660
4e5f 0N7Polymerase acidic protein / 0.660
4fkj 11KCyclin-dependent kinase 2 2.7.11.22 0.660
3zmm F9JTyrosine-protein kinase JAK2 / 0.657
4fki 09KCyclin-dependent kinase 2 2.7.11.22 0.657
3lfs A07Cyclin-dependent kinase 2 2.7.11.22 0.653
2qhn 582Serine/threonine-protein kinase Chk1 2.7.11.1 0.652
3le6 2BZCyclin-dependent kinase 2 2.7.11.22 0.652
3nun JMZ3-phosphoinositide-dependent protein kinase 1 2.7.11.1 0.652
2x4z X4ZSerine/threonine-protein kinase PAK 4 2.7.11.1 0.651
4nks 2M2Fibroblast growth factor receptor 1 / 0.651