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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ayy 9MX Prothrombin 3.4.21.5

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ayy 9MXProthrombin 3.4.21.5 1.088
4ax9 N5NProthrombin 3.4.21.5 0.843
4az2 9MUProthrombin 3.4.21.5 0.841
4ayv 9MQProthrombin 3.4.21.5 0.829
1k21 IGNProthrombin 3.4.21.5 0.795
1k22 MELProthrombin 3.4.21.5 0.781
1o0d 163Prothrombin 3.4.21.5 0.772
4baq M4ZProthrombin 3.4.21.5 0.772
2bdy UNBProthrombin 3.4.21.5 0.763
4bak M67Prothrombin 3.4.21.5 0.762
4ban M6SProthrombin 3.4.21.5 0.762
1vzq SHYProthrombin 3.4.21.5 0.760
1ypg UIRProthrombin 3.4.21.5 0.758
1ypj UIBProthrombin 3.4.21.5 0.758
4bah MELProthrombin 3.4.21.5 0.758
4bao MVFProthrombin 3.4.21.5 0.757
2cf9 348Prothrombin 3.4.21.5 0.755
2zgx 29UProthrombin 3.4.21.5 0.754
1d4p BPPProthrombin 3.4.21.5 0.752
2zhf 49UProthrombin 3.4.21.5 0.752
1ypm RA4Prothrombin 3.4.21.5 0.751
2ziq 26UProthrombin 3.4.21.5 0.751
3utu 1TSProthrombin 3.4.21.5 0.751
2cf8 ESHProthrombin 3.4.21.5 0.750
2zda 32UProthrombin 3.4.21.5 0.745
2zfr 46UProthrombin 3.4.21.5 0.745
2v3h I25Prothrombin 3.4.21.5 0.743
1ype UIPProthrombin 3.4.21.5 0.741
2zhe 13UProthrombin 3.4.21.5 0.738
4e7r 0NWProthrombin 3.4.21.5 0.736
2zfq 45UProthrombin 3.4.21.5 0.732
1c5n ESIProthrombin 3.4.21.5 0.731
2anm CDOProthrombin 3.4.21.5 0.731
2gde SN3Prothrombin 3.4.21.5 0.730
4bam MM9Prothrombin 3.4.21.5 0.730
2cn0 F25Prothrombin 3.4.21.5 0.729
7kme ACE_0BN_CHG_PRRProthrombin 3.4.21.5 0.728
1c4u IH1Prothrombin 3.4.21.5 0.725
2zi2 24UProthrombin 3.4.21.5 0.725
1riw OSCProthrombin 3.4.21.5 0.721
3biv 11UProthrombin 3.4.21.5 0.717
3hat GLY_VAL_ARG_RNGProthrombin 3.4.21.5 0.717
1nzq 162Prothrombin 3.4.21.5 0.716
1uvs I11Prothrombin 3.4.21.5 0.715
2a2x NA9Prothrombin 3.4.21.5 0.710
1ghv 120Prothrombin 3.4.21.5 0.706
1ypl RA8Prothrombin 3.4.21.5 0.704
1oyt FSNProthrombin 3.4.21.5 0.703
1ypk CCRProthrombin 3.4.21.5 0.697
5cmx 0G6Prothrombin 3.4.21.5 0.697
1gj5 130Prothrombin 3.4.21.5 0.696
1c4v IH2Prothrombin 3.4.21.5 0.693
1lpk CBBCoagulation factor X 3.4.21.6 0.691
2pks G44Prothrombin 3.4.21.5 0.688
1ta2 176Prothrombin 3.4.21.5 0.684
1ta6 177Prothrombin 3.4.21.5 0.684
2znk 31UProthrombin 3.4.21.5 0.684
1z71 L17Prothrombin 3.4.21.5 0.681
1c1u BAIProthrombin 3.4.21.5 0.676
2zhw 12UProthrombin 3.4.21.5 0.676
1nt1 T76Prothrombin 3.4.21.5 0.674
1f92 UKPUrokinase-type plasminogen activator 3.4.21.73 0.671
2bok 784Coagulation factor X 3.4.21.6 0.670
2zg0 50UProthrombin 3.4.21.5 0.667
2bvs 2CEProthrombin 3.4.21.5 0.663
1kts C24Prothrombin 3.4.21.5 0.662
3dux 64UProthrombin 3.4.21.5 0.658
2zp0 PI0Coagulation factor VII 3.4.21.21 0.657
2zf0 51UProthrombin 3.4.21.5 0.656
1nm6 L86Prothrombin 3.4.21.5 0.653
2zhq 27UProthrombin 3.4.21.5 0.653
2jh0 701Prothrombin 3.4.21.5 0.652
2zfp 19UProthrombin 3.4.21.5 0.651