Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4asd BAX Vascular endothelial growth factor receptor 2 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4asd BAXVascular endothelial growth factor receptor 2 2.7.10.1 1.285
3wze BAXVascular endothelial growth factor receptor 2 2.7.10.1 1.109
2xir 00JVascular endothelial growth factor receptor 2 2.7.10.1 0.833
2hzn KINTyrosine-protein kinase ABL1 2.7.10.2 0.824
3gcs BAXMitogen-activated protein kinase 14 / 0.822
5hi2 BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.818
3ugc 046Tyrosine-protein kinase JAK2 / 0.816
3b8q 900Vascular endothelial growth factor receptor 2 2.7.10.1 0.802
3b8r 887Vascular endothelial growth factor receptor 2 2.7.10.1 0.791
2oh4 GIGVascular endothelial growth factor receptor 2 2.7.10.1 0.768
3qri 919Tyrosine-protein kinase ABL1 2.7.10.2 0.760
4u0i 0LIMast/stem cell growth factor receptor Kit 2.7.10.1 0.759
4v01 0LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b / 0.759
2rl5 2RLVascular endothelial growth factor receptor 2 2.7.10.1 0.753
2ofv 242Tyrosine-protein kinase Lck 2.7.10.2 0.749
4tyj 0LIFibroblast growth factor receptor 4 2.7.10.1 0.735
2hz0 GINTyrosine-protein kinase ABL1 2.7.10.2 0.730
1uwh BAXSerine/threonine-protein kinase B-raf 2.7.11.1 0.725
4uxq 0LIFibroblast growth factor receptor 4 2.7.10.1 0.717
1ywn LIFVascular endothelial growth factor receptor 2 2.7.10.1 0.710
3vhe 42QVascular endothelial growth factor receptor 2 2.7.10.1 0.709
4neu Q1AReceptor-interacting serine/threonine-protein kinase 1 2.7.11.1 0.709
4at4 T6EBDNF/NT-3 growth factors receptor 2.7.10.1 0.707
3b2w 9NHTyrosine-protein kinase Lck 2.7.10.2 0.702
3el8 PD5Proto-oncogene tyrosine-protein kinase Src 2.7.10.2 0.692
3dko IHZEphrin type-A receptor 7 2.7.10.1 0.688
4o2z 046Mitogen-activated protein kinase / 0.685
3o8u BMUMitogen-activated protein kinase 14 / 0.682
4eyj N61Mitogen-activated protein kinase 13 2.7.11.24 0.682
3gi3 B10Mitogen-activated protein kinase 14 / 0.678
3vnt 0JAVascular endothelial growth factor receptor 2 2.7.10.1 0.675
2yis YISMitogen-activated protein kinase 14 / 0.671
3be2 RAJVascular endothelial growth factor receptor 2 2.7.10.1 0.668
3hv3 R49Mitogen-activated protein kinase 14 / 0.665
3nnx EDDMitogen-activated protein kinase 14 / 0.665
4h1m 0YJProtein-tyrosine kinase 2-beta 2.7.10.2 0.663
1kv1 BMUMitogen-activated protein kinase 14 / 0.662
2puu G2GMitogen-activated protein kinase 14 / 0.661
3gcq 1BUMitogen-activated protein kinase 14 / 0.660
3oc1 BMUMitogen-activated protein kinase 14 / 0.660
3uvr 06FMitogen-activated protein kinase 14 / 0.660
3cs9 NILTyrosine-protein kinase ABL1 2.7.10.2 0.658
1kv2 B96Mitogen-activated protein kinase 14 / 0.653
3o8p BMUMitogen-activated protein kinase 14 / 0.651
3hv6 R39Mitogen-activated protein kinase 14 / 0.650