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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4ap7 F47 Hepatocyte growth factor receptor 2.7.10.1

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4ap7 F47Hepatocyte growth factor receptor 2.7.10.1 0.935
3zbx 6XEHepatocyte growth factor receptor 2.7.10.1 0.824
3zze 6XPHepatocyte growth factor receptor 2.7.10.1 0.739
3zc5 W9ZHepatocyte growth factor receptor 2.7.10.1 0.738
4aoi 4K0Hepatocyte growth factor receptor 2.7.10.1 0.702
3qzg X67Cyclin-dependent kinase 2 2.7.11.22 0.662
2xm9 LWHSerine/threonine-protein kinase Chk2 2.7.11.1 0.651