Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4an3 5Y0 Dual specificity mitogen-activated protein kinase kinase 1 2.7.12.2

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity		 Align
4an3 5Y0Dual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 1.094
3vvh 4BMDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.914
4an9 2P7Dual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.881
4anb YQYDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.852
3dv3 MEKDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.831
3orn 3ORDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.816
1s9j BBMDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.792
4an2 EUIDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.781
3dy7 1CXDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.743
3e8n VRADual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.740
3os3 3OSDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.727
4e5l DBHPolymerase acidic protein / 0.694
3sls 77DDual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.680
3v04 V04Dual specificity mitogen-activated protein kinase kinase 1 2.7.12.2 0.666